P4032
プロテイナーゼ from Aspergillus melleus
Type XXIII, ≥3 units/mg solid
別名:
プロテアーゼM「アマノ」
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この商品について
CAS番号:
UNSPSC Code:
12352204
eCl@ss:
32160410
EC Number:
232-642-4
NACRES:
NA.54
MDL number:
Specific activity:
≥3 units/mg solid
Biological source:
Aspergillus sp. (A. melleus)
Application
Proteinase is an enzyme used to break down proteins by hydrolyzing peptide bonds. Proteinase is used to degrade proteins, to study proteinase inhibitors and to study thermal inactivation kinetics. Proteinase is used in nucleic acid isolation procedures in incubations. It is used to study proteinase-activated receptors, such as the transducers of proteinase-mediated signaling in inflammation and the immune response. Product P4032 is from Aspergillus melleus and has been used to non-specifically degraded xylanase from Streptomyces halstedii.
Biochem/physiol Actions
Proteinase catabolizes proteins by hydrolysis of peptide bonds. Proteases are inactivated by serine active-site inhibitors, such as phenylmethylsulfonyl fluoride (PMSF) and diisopropylfluorophosphate .
Other Notes
1ユニットは、特記しない限り、pH 7.5、37°C、1分間で、カゼインを加水分解し1.0 μmol(181 μg)のチロシンに相当する呈色を生ずる量です(Folin-Ciocalteau試薬で発色)。
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
P4032-100G: + P4032-BULK: + P4032-5G: + P4032-VAR: + P4032-25G:
jan
Ravindra S Prajapati et al.
Development (Cambridge, England), 146(24) (2019-12-07)
During early embryogenesis, the ectoderm is rapidly subdivided into neural, neural crest and sensory progenitors. How the onset of lineage determinants and the loss of pluripotency markers are temporally and spatially coordinated in vivo is still debated. Here, we identify
Mikhail E Kandel et al.
Nature communications, 10(1), 4691-4691 (2019-10-18)
Multiple scattering and absorption limit the depth at which biological tissues can be imaged with light. In thick unlabeled specimens, multiple scattering randomizes the phase of the field and absorption attenuates light that travels long optical paths. These obstacles limit
Chenzhong Yin et al.
Scientific reports, 10(1), 15078-15078 (2020-09-17)
Understanding the mechanisms by which neurons create or suppress connections to enable communication in brain-derived neuronal cultures can inform how learning, cognition and creative behavior emerge. While prior studies have shown that neuronal cultures possess self-organizing criticality properties, we further
Martin Steinhoff et al.
Endocrine reviews, 26(1), 1-43 (2005-02-04)
Serine proteinases such as thrombin, mast cell tryptase, trypsin, or cathepsin G, for example, are highly active mediators with diverse biological activities. So far, proteinases have been considered to act primarily as degradative enzymes in the extracellular space. However, their
Laura E Mickelsen et al.
eLife, 9 (2020-10-30)
The ventral posterior hypothalamus (VPH) is an anatomically complex brain region implicated in arousal, reproduction, energy balance, and memory processing. However, neuronal cell type diversity within the VPH is poorly understood, an impediment to deconstructing the roles of distinct VPH
関連コンテンツ
QC Methods
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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