PHG0010
イソプロピル β-D-1-チオガラクトピラノシド
別名:
IPTG, イソプロピル β-D-チオガラクトシド
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この商品について
実験式（ヒル表記法）:
C9H18O5S
CAS番号:
分子量:
238.30
EC Number:
206-703-0
UNSPSC Code:
12352201
MDL number:
Beilstein/REAXYS Number:
4631
InChI
1S/C9H18O5S/c1-4(2)15-9-8(13)7(12)6(11)5(3-10)14-9/h4-13H,3H2,1-2H3/t5-,6+,7+,8-,9+/m1/s1
InChI key
BPHPUYQFMNQIOC-NXRLNHOXSA-N
SMILES string
CC(C)S[C@@H]1OC(CO)[C@H](O)C(O)[C@H]1O
biological source
synthetic
form
powder
storage temp.
2-8°C
Quality Level
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General description
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
Application
IPTGは、β-ガラクトシダーゼ活性の発現誘導が必要なクローニングの際に用いられます。大腸菌中のlacオペロンの発現を誘導させる組み換えコロニーのblue-white selectionの際に、X-GalまたはBluo-Gal とともに用います。β-ガラクトシダーゼをコードしているlacZ遺伝子を抑制しているlacIリプレッサーに結合してコンホメーションを変化させ、その抑制を妨げます。
Other Notes
代謝されないグルコースのアナログです。
Legal Information
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
PHG0010-VAR: + PHG0010-5G-PW: + PHG0010-5G: + PHG0010-BULK: + PHG0010-1000G: + PHG0010-100G: + PHG0010-1000G-PW: + PHG0010-100G-PW: + PHG0010-25G: + PHG0010-25G-PW:
jan
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Microglia are tissue macrophages of the central nervous system (CNS) that control tissue homeostasis. Microglia dysregulation is thought to be causal for a group of neuropsychiatric, neurodegenerative and neuroinflammatory diseases, called "microgliopathies". However, how the intracellular stimulation machinery in microglia
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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