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Merck

1.41544

Parteck® MXP (Polyvinyl alcohol 3-82)

EMPROVE® ESSENTIAL, Ph. Eur.

동의어(들):

Parteck® Polyvinyl alcohol, PVA, Polyvinyl alcohol

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
(C2H4O)n
CAS 번호:
9002-89-5
UNSPSC Code:
12352104
MDL number:
MFCD00081922

주요 문서

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제품 이름

Parteck® MXP (Polyvinyl alcohol 3-82), EMPROVE® ESSENTIAL, Ph. Eur.

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

agency

Ph. Eur.

product line

EMPROVE® ESSENTIAL

form

powder

application(s)

pharmaceutical
solid formulation
solubility enhancement

storage temp.

15-25°C

Quality Level

500

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관련 카테고리

Application

Parteck® MXP 3-82 is a PVA-based excipient that is used in Hot Melt Extrusion for Solubility Enhancement in oral solid dosage forms.

Features and Benefits

  • Superior supersaturation performance via precipitation inhibition
  • High thermostability up to 250°C, extending the potential application range
  • Stable high drug loads and suitability with a broad range of APIs
  • Flexible release kinetics
  • Compatible with several downstream processing capabilities, like direct compression, continuous manufacturing, thin film extrusion and 3D printing
  • Optimized powder properties for excellent performance in the HME process
  • Suitable polymer properties for HME, spray drying and 3D printing processes

General description

With a lower degree of hydrolysis along the PVA chain, Parteck® MXP 3-82 Polyvinyl alcohol is especially beneficial in forming strong interac­tions with hydrophobic drug molecules – in the solid state and in solution. Due to this, Parteck® MXP 3-82 excipient has very high capabilities as a precipitation inhibitor and can maintain high levels of supersaturation for physiologi­cally relevant timescales. As a result, Parteck® MXP 3-82 Polyvinyl alcohol can provide solubility enhancement for even the most challenging molecules.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

No data available

flash_point_c

No data available

시험 성적서(COA)

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Improving API Solubility Using Spray Drying with Polyvinyl Alcohol

Discover how spray drying with polyvinyl alcohol enhances solubility for small and large molecule drugs and unlocks the potential of poorly soluble APIs.

Solid Formulation Development Using Melt-based 3D Printing Technologies

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국제 무역 품목 번호

SKUGTIN
1.41544.100004065266953343

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