SMILES string
ClC(=CCl)Cl
InChI key
XSTXAVWGXDQKEL-UHFFFAOYSA-N
InChI
1S/C2HCl3/c3-1-2(4)5/h1H
grade
pharmaceutical primary standard
form
solution
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
single component solution
Related Categories
General description
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Residual Solvent Class 2 - Trichloroethylene USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Danger
target_organs
Central nervous system
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
closed cup - does not flash
flash_point_c
closed cup - does not flash
Hazard Classifications
Aquatic Chronic 3 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1B - STOT SE 3
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Michihiro Kamijima et al.
International archives of occupational and environmental health, 80(5), 357-370 (2006-11-16)
Workers exposed to trichloroethylene (TCE) rarely show severe generalized skin disorders and accompanying hepatitis which resemble drug hypersensitivities. The disorders are completely different from solvent-induced irritating contact dermatitis, and their serious consequences have become one of the critical occupational health
Hideaki Watanabe et al.
Dermatology (Basel, Switzerland), 221(1), 17-22 (2010-04-22)
Patients having a generalised rash with severe liver dysfunction associated with exposure to trichloroethylene (TCE) have been reported mainly in Asian countries. However, no case has been reported in Japan since the 1990s. Here, we describe a case of hypersensitivity
Hang Zhang et al.
Biochemical and biophysical research communications, 446(2), 590-595 (2014-03-19)
Trichloroethylene (TCE), a major occupational and environmental pollutant, has been recently associated with aberrant epigenetic changes in experimental animals and cultured cells. TCE is known to cause severe hepatotoxicity; however, the association between epigenetic alterations and TCE-induced hepatotoxicity are not
Prabhakar Pant et al.
Journal of environmental sciences (China), 22(1), 116-126 (2010-04-20)
Research works in the recent past have revealed three major biodegradation processes leading to the degradation of trichloroethylene. Reductive dechlorination is an anaerobic process in which chlorinated ethenes are used as electron acceptors. On the other hand, cometabolism requires oxygen
Amy Lavin Williams et al.
International journal of toxicology, 27(1), 81-95 (2008-02-23)
An evaluation of the scientific literature for trichloroethylene (TCE) identified two reports of ocular defects, specifically microphthalmia/anophthalmia, following prenatal TCE exposure in rats. Herein, these reports are analyzed in detail and interpreted within the context of other developmental TCE exposure
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