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Merck

PHR1133

Cetyl Alcohol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

1-Hexadecanol, Cetyl alcohol, Palmityl alcohol

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A propos de cet article

Formule linéaire :
CH3(CH2)15OH
Numéro CAS:
Poids moléculaire :
242.44
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
253-149-0
Beilstein/REAXYS Number:
1748475
MDL number:
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Nom du produit

Cetyl Alcohol, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/C16H34O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h17H,2-16H2,1H3

InChI key

BXWNKGSJHAJOGX-UHFFFAOYSA-N

SMILES string

CCCCCCCCCCCCCCCCO

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. C0990000
traceable to USP 1103003

vapor density

8.34 (vs air)

vapor pressure

<0.01 mmHg ( 43 °C)

API family

cetyl alcohol

CofA

current certificate can be downloaded

autoignition temp.

483 °F

expl. lim.

8 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

179-181 °C/10 mmHg (lit.)

mp

48-50 °C (lit.)

density

0.818 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Application

Cetyl Alcohol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7153 in the slot below. This is an example certificate only and may not be the lot that you receive.

Classe de stockage

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

The application of chromatography to the analysis of pharmaceutical creams.
Van de Vaart FJ, et al.
Chromatographia, 16(1), 247-250 (1982)
HPLC-fluorescence determination of chlorocresol and chloroxylenol in pharmaceuticals.
Gatti R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 16(3), 405-412 (1997)
Flávia C Carvalho et al.
Journal of pharmaceutical sciences, 99(5), 2367-2374 (2009-12-08)
The development of a controlled-release dosage form of zidovudine (AZT) is of crucial importance, in view of the pharmacokinetics of its toxic activity. A suitable drug delivery system could increase AZT bioavailability, reducing its dose-dependent side effects. In this study
Dhanalakshmi S Anbukumar et al.
Journal of lipid research, 51(5), 1085-1092 (2009-12-19)
Neutrophils are important in the host response against invading pathogens. One chemical defense mechanism employed by neutrophils involves the production of myeloperoxidase (MPO)-derived HOCl. 2-Chlorohexadecanal (2-ClHDA) is a naturally occurring lipid product of HOCl targeting the vinyl ether bond of
Laurent Perge et al.
International journal of pharmaceutics, 422(1-2), 59-67 (2011-10-27)
A hot melt dispersion method was used to prepare new sustained release ibuprofen composite microparticles of a solid lipid at ambient temperature, cetyl alcohol. The dispersion of colloidal silicon dioxide nanoparticles (hydrophilic Aerosil 200 or hydrophobic Aerosil R974) either in

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