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ABS434 Anti-ApoA4 Antibody

Anti-ApoA4 Antibody is a highly specific rabbit polyclonal antibody, that targets Apolipoprotein A & has been tested in western blotting & IHC.

Anti-ApoA4 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Lipid Metabolism & Weight Regulation Gene Symbol: APOA4 UniProt Number: P06727
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ABS434
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS434
      DescriptionAnti-ApoA4 Antibody
      Alternate Names
      • Apolipoprotein A4
      • Apolipoprotein A-IV
      • ApoA-IV
      • APO-AIV
      • ApoA4
      Background InformationApoA4, also known as Apolipoprotein A4 or ApoA-IV, is a member of the apolipoprotein A1/A4/E family. ApoA4 is a major component of HDL and it can be found on the surface of newly synthesized chylomicrons. Studies have shown that APoA4 is required for efficient activation of lipoprotein lipase by ApoC-II, which is a potent activator of Lecithin Cholesterol Acyltransferase (LCAT). Other evidence points out that ApoA4 may have a role in chylomicrons and VLDL secretion and catabolism. The physiological function of ApoA4 is not confirmed yet, but evidence from several in vitro studies indicate that it may play a role in the reverse cholesterol transport pathway, transporting cholesterol from peripheral cells back to the liver. ApoA4 is synthesized primarily in the intestine and secreted in the plasma.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human liver tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-ApoA4 Antibody is a highly specific rabbit polyclonal antibody, that targets Apolipoprotein A & has been tested in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected ApoA4 in human colon tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human ApoA4.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • APOA4
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~38 kDa observed. Uncharacterized bands may appear in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human liver tissue lysate.

      Western Blotting Analysis: 2 µg/mL of this antibody detected ApoA4 in 15 µg of human liver tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABS434 04053252923517