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ABN334 Anti-SAPAP4 Antibody

This SAPAP4 antibody is validated for use in WB & IHC for the detection of the SAPAP4 protein.

Anti-SAPAP4 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: DLGAP4 UniProt Number: Q9Y2H0
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ABN334
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN334
      DescriptionAnti-SAPAP4 Antibody
      Alternate Names
      • SAPAP4
      • SAP90
      • PSD-95-associated protein 4
      • Disks large-associated protein 4
      • DLGAP4
      • DAP4
      Background InformationSAP90/PSD-95-associated protein 4 (SAPAP4, also known as DLGAP4) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP4 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP4 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -2, whereas SAPAP3 mRNA is detected mainly in cell bodies. At least three isoforms of SAPAP4 are known to exist.
      References
      Product Information
      FormatAffinity Purified
      Control
      • SK-N-SH cell lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationThis SAPAP4 antibody is validated for use in WB & IHC for the detection of the SAPAP4 protein.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:500 dilution from a representative lot detected SAPAP4 in rat hippocampus tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human SAPAP4.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis SAPAP4 antibody will not cross-react with other SAPAP proteins.
      Species Reactivity
      • Human
      • Rat
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • DLGAP4
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~138 kDa observed. The calculated molecular weight of this protein is 109 kDa, but can be observed at ~138 kDa due to post translational modification.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in SK-N-SH cell lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected SAPAP4 in 15 µg/mL of SK-N-SH cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN334 04053252831140