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852067 Fmoc-Arg(Pbf)-OH

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
154445-77-9C₃₄H₄₀N₄O₇S648.77 g/mol

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                      Description
                      Catalogue Number852067
                      Replaces04-12-1145
                      Brand Family Novabiochem®
                      Alternate Names
                      • N-α-Fmoc-NG-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
                      Background InformationThe standard derivative for the introduction of Arg in Fmoc SPPS [1, 2]. The Pbf side-chain protecting group is removed with TFA approximately 1-2 times faster than Pmc.

                      In the preparation of peptides containing both Arg and Trp, it is recommended that this derivative is used in conjunction with Fmoc-Trp(Boc)-OH (852050).

                      The product number for this product was previously 04-12-1145.

                      To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
                      References
                      Product Information
                      CAS number154445-77-9
                      Hill FormulaC₃₄H₄₀N₄O₇S
                      Molar Mass648.77 g/mol
                      HS Code2935 90 29
                      Structure formula ImageStructure formula Image
                      Quality LevelMQ400
                      Applications
                      ApplicationFmoc-Arg(Pbf)-OH Novabiochem®. CAS 154445-77-9, molar mass 648.78 g/mol.
                      Biological Information
                      Physicochemical Information
                      Melting Point>65 °C
                      Dimensions
                      Materials Information
                      Toxicological Information
                      Safety Information according to GHS
                      Storage class10 - 13 Other liquids and solids
                      WGKWGK 3 highly hazardous to water
                      Safety Information
                      Product Usage Statements
                      Storage and Shipping Information
                      StorageStore at -10°C to -25°C.
                      Packaging Information
                      Transport Information
                      Supplemental Information
                      Specifications
                      Color (visual)white to off white
                      Appearance of substance (visual)powder
                      Color index (0,5 M in DMF)≤ 150 Hazen
                      Identity (IR)passes test
                      Enantiomeric purity≥ 99.8 % (a/a)
                      Purity (HPLC)≥ 99.0 % (a/a)
                      Fmoc-ß-Ala-OH (HPLC)≤ 0.1 % (a/a)
                      Fmoc-ß-Ala-Arg(Pbf)-OH (HPLC)≤ 0.1 % (a/a)
                      Fmoc-Arg(Pbf)-Arg(Pbf)-OH (HPLC)≤ 0.1 % (a/a)
                      Fmoc-Arg-OH (HPLC)≤ 0.1 % (a/a)
                      Assay free amino acid (HPLC)≤ 0.2 %
                      Purity (TLC(011C))≥ 98 %
                      Purity (TLC(157B))≥ 98 %
                      Solubility (12,5 mmol in 25 ml DMF)clearly soluble
                      Assay (acidimetric)≥ 90.0 %
                      Water (K. F.)≤ 2.0 %
                      Ethyl acetate (HS-GC)≤ 1.0 %
                      Acetate (IC)≤ 0.02 %
                      For TLC-Systems see our General Catalog
                      Global Trade Item Number
                      Catalogue Number GTIN
                      8520670005 04027269087982
                      8520670025 04027269087999
                      8520670100 04027269088002
                      8520670250 04027269207076
                      8520671000 04027269180478

                      Documentation

                      Fmoc-Arg(Pbf)-OH SDS

                      Title

                      Safety Data Sheet (SDS) 

                      Citations

                      Title
                      • [1] L. A. Carpino, et al. (1993) Tetrahedron Lett., 34, 7829.
                      • [2] C. G. Fields, et al. (1993) Tetrahedron Lett., 34, 6661.