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852113 Fmoc-Asp(biotinyl-PEG)-OH

Overview

Replacement Information

Key Spec Table

Hill FormulaMolar Mass
C₃₉H₅₃N₅O₁₀S783.93 g/mol

Pricing & Availability

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8521130001
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      Glass bottle 1 g
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      8521138500
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          Glass bottle 500 mg
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          Description
          Catalogue Number852113
          Replaces04-12-1279
          Brand Family Novabiochem®
          Alternate Names
          • N-α-Fmoc-N-γ-(N-biotinyl-3-(2-(2-(3-aminopropyloxy)-ethoxy)-ethoxy)-propyl)-L-asparagine
          Background InformationIn contrast to Fmoc-Lys(biotin)-OH, this novel biotin-labeled amino acid has excellent solubility in DMF and other solvents used in SPPS [1]. The PEG-spacer restricts hindrance between the peptide and avidin, leading to better biotin binding. Furthermore, the hydrophilic nature of the PEG minimizes non-specific interactions that can arise from the spacer group becoming buried in the hydrophobic pocket of proteins.

          The product number for this product was previously 04-12-1279.

          To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
          References
          Product Information
          Hill FormulaC₃₉H₅₃N₅O₁₀S
          Molar Mass783.93 g/mol
          HS Code2934 99 90
          Structure formula ImageStructure formula Image
          Quality LevelMQ200
          Applications
          Biological Information
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Storage class10 - 13 Other liquids and solids
          WGKWGK 2 obviously hazardous to water
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +2°C to +8°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Color (visual)white to slight yellow to beige
          Appearance of substance (visual)powder
          Identity (IR)passes test
          Enantiomeric purity≥ 99.5 % (a/a)
          Purity (TLC(CMA2))≥ 98 %
          Assay (HPLC, area%)≥ 95.0 % (a/a)
          Solubility (1 mmole in 2 ml DMF)clearly soluble
          For TLC-Systems see our General Catalog
          Global Trade Item Number
          Catalogue Number GTIN
          8521130001 04027269089870
          8521138500 04027269089887

          Documentation

          Fmoc-Asp(biotinyl-PEG)-OH SDS

          Title

          Safety Data Sheet (SDS) 

          Citations

          Title
          [1] B. Baumeister, et al. (2003) Biopolymers, 71, 339.

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          Categories

          Reagents, Chemicals and Labware > Novabiochem® Peptide and DNA Synthesis Reagents > Derivatives for Peptide Labeling > Biotinylating Derivatives
          Reagents, Chemicals and Labware > Novabiochem® Peptide and DNA Synthesis Reagents > Derivatives for Peptide Labeling > Chromogenic Derivatives
          Reagents, Chemicals and Labware > Novabiochem® Peptide and DNA Synthesis Reagents > Building Blocks for Solid Phase Peptide Synthesis > Fmoc-amino Acids > Aspartic acid [Asp, D]