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368056 Granzyme B Inhibitor IV - Calbiochem

The Granzyme B Inhibitor IV controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.

Granzyme B Inhibitor IV - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Ac-IEPD-CHO, Caspase-8 inhibitor III

Primary Target: granzyme B
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368056
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₂H₃₄N₄O₉

Pricing & Availability

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368056-1MG
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      		 Plastic ampoule 1 mg
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      Description
      OverviewA reversible inhibitor of granzyme B and caspase-8.
      Catalogue Number368056
      Brand Family Calbiochem®
      SynonymsAc-IEPD-CHO, Caspase-8 inhibitor III
      References
      ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
      Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
      Product Information
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₂H₃₄N₄O₉
      Chemical formulaC₂₂H₃₄N₄O₉
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetgranzyme B
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceAc-Ile-Glu-Pro-Asp-CHO
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      368056-1MG 04055977192148

      Documentation

      Granzyme B Inhibitor IV - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Granzyme B Inhibitor IV - Calbiochem Certificates of Analysis

      TitleLot Number
      368056

      References

      Reference overview
      Harris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
      Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-July-2008 RFH
      SynonymsAc-IEPD-CHO, Caspase-8 inhibitor III
      DescriptionA reversible inhibitor of Granzyme B that also inhibits caspase-8. Granzyme B is a protease involved in the induction of rapid target cell death by cytotoxic lymphocytes.
      FormWhite solid
      Chemical formulaC₂₂H₃₄N₄O₉
      Peptide SequenceAc-Ile-Glu-Pro-Asp-CHO
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
      Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.