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855074 Weinreb AM resin

Overview

Replacement Information

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8550740001
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      Plastic bottle 1 g
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      8550740005
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          Plastic bottle 5 g
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          8550740025
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              Plastic bottle 25 g
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              Description
              Catalogue Number855074
              Replaces01-64-0153
              Brand Family Novabiochem®
              Alternate Names
              • N-Fmoc- N-methoxy-β-alanine AM resin
              Background InformationThis support is useful for the production of peptide aldehydes and other carboxaldehydes. Following removal of the Fmoc group with 20% piperidine in DMF, acylation of the resin-bound methoxylamine is best effected using DIPCDI/HOAt or HATU/DIPEA activation. This results in formation of a supported Weinreb-type amide which can be either reduced to an aldehyde with LiAlH4 [1, 2] or cleaved with Grignard reagents to give ketones [2, 3].

              The product number for this product was previously 01-64-0153.

              To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
              References
              Product Information
              HS Code3903 90 90
              Structure formula ImageStructure formula Image
              Quality LevelMQ200
              Applications
              Biological Information
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Storage class10 - 13 Other liquids and solids
              WGKWGK 1 slightly hazardous to water
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              StorageStore below +30°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Color (visual)white to yellow to beige
              Appearance of substance (visual)beads
              Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF)0.40 - 1.00 mmol/g
              Swelling Volume (in CH₂Cl₂)lot specific result
              The polymer matrix is copoly (styrene - 1 % DVB), 100 - 200 mesh
              Global Trade Item Number
              Catalogue Number GTIN
              8550740001 04027269112530
              8550740005 04027269112547
              8550740025 04027269112554

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              Categories

              Reagents, Chemicals and Labware > Novabiochem® Peptide and DNA Synthesis Reagents > Resins for Solid Phase Peptide Synthesis > Resins for Fmoc SPPS of Carboxy-modified Peptides > Peptide Aldehydes
              Reagents, Chemicals and Labware > Novabiochem® Peptide and DNA Synthesis Reagents > Resins for Solid Phase Organic Chemistry > NH2, NH2NH Functionalized Resins > Resins Cleaved by Hydrides and Organometallic Reagents