116802 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt - CAS 30275-80-0 - Calbiochem

116802
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Empirical FormulaCAS #
C₁₇H₁₅N₅O₇P · Na 30275-80-0

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116802-10UMOL
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      Description
      OverviewA potent cell-permeable activator of cAMP-dependent protein kinase (PKA). Activates both type 1 and type 2 PKA and binds to the cAMP binding site 2 on the regulatory subunit of PKA. It is only slowly metabolized by cyclic nucleotide-dependent phosphodiesterases. Due to its considerably increased lipophilicity, it has sufficient membrane permeability for many biological systems.
      Note: 10 µmol = 4.55 mg.
      Catalogue Number116802
      Brand Family Calbiochem®
      Synonyms6-Bnz-cAMP, Na
      References
      ReferencesDøskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249.
      Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555.
      Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.
      Product Information
      CAS number30275-80-0
      ATP CompetitiveN
      FormLyophilized
      Hill FormulaC₁₇H₁₅N₅O₇P · Na
      Chemical formulaC₁₇H₁₅N₅O₇P · Na
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationAdenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt, CAS 30275-80-0, is a cell-permeable, potent activator of PKA type 1 & 2. Binds to the cAMP binding site 2 on the regulatory unit of PKA.
      Biological Information
      Primary TargetPKA
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt - CAS 30275-80-0 - Calbiochem FDS

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      Fiche de données de sécurité des matériaux (FDS) 

      Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt - CAS 30275-80-0 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      116802

      Références bibliographiques

      Aperçu de la référence bibliographique
      Døskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249.
      Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555.
      Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-September-2007 RFH
      Synonyms6-Bnz-cAMP, Na
      DescriptionA potent, non-degradable, cell-permeable analog of cAMP that binds to the cAMP binding site 2 on the protein kinase A (PKA) regulatory subunit and activates both type I and II PKA. λmax = 279 nm (H2O, pH 7.0); εmax = 17,000 M-1cm-1.
      FormLyophilized
      CAS number30275-80-0
      Chemical formulaC₁₇H₁₅N₅O₇P · Na
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O (10 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesDøskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249.
      Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555.
      Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.