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ABN200 Anti-C-X-C chemokine receptor type 5 (CXCR5) Antibody

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ABN200
100 µg  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN200
      DescriptionAnti-C-X-C chemokine receptor type 5 (CXCR5) Antibody
      Alternate Names
      • C-X-C chemokine receptor type 5
      • CXC-R5
      • CXCR-5
      • Burkitt lymphoma receptor 1
      • Monocyte-derived receptor 15
      • MDR-15
      • CD185
      Background InformationC-X-C chemokine receptor type 5 (CXCR5; Burkitt lymphoma receptor 1; Monocyte-derived receptor 15) is a G-protein coupled cytokine receptor that binds selectively to the CXCL13 (B lymphocyte chemoattractant) ligand, and mediates the development and function of the immune system. It is expressed in mature B cells, and facilitates the migration of B cells into follicles of the splenic white pulp, and enables deposition of antigen on follicular dendritic cells. It is also involved in the development of lymph nodes and Peyer’s patches. Previous studies have reported that the expression of CXCR5 increases in rheumatoid arthritis.
      References
      Product Information
      FormatAffinity Purified
      Control
      • SH-SY5Y cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-C-X-C chemokine receptor type 5 (CXCR5) Antibody is an antibody against C-X-C chemokine receptor type 5 (CXCR5) for use in Western Blotting, IHC(P).
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from representative lot detected C-X-C chemokine receptor type 5 (CXCR5) in mouse frontal cortex neurons and mouse spleen lymphocytes.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the cytoplasmic domain of human C-X-C chemokine receptor type 5 (CXCR5).
      EpitopeCytoplasmic domain
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the cytoplasmic domain of C-X-C chemokine receptor type 5 (CXCR5).
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CXCR5
      • BLR1
      • MDR15
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~51 / 38 kDa observed. Uniprot describes 2 isoforms produced by alternative splicing with molecular weights ~42 and ~37 kDa. The calculated molecular weight of this protein is 42 kDa, but can be observed at ~51 kDa due to high glycosylation.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in SH-SY5Y cell lysate.

      Western Blot Analysis: 0.1 µg/mL of this antibody detected C-X-C chemokine receptor type 5 (CXCR5) in 10 µg of SH-SY5Y cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      ABN200 04053252696732

      Documentation

      Anti-C-X-C chemokine receptor type 5 (CXCR5) Antibody FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Anti-C-X-C chemokine receptor type 5 (CXCR5) Antibody Certificats d'analyse

      TitreNuméro de lot
      Anti-C-X-C chemokine receptor type 5 (CXCR5) - 2395797 2395797
      Anti-C-X-C chemokine receptor type 5 (CXCR5) - 3482851 3482851
      Anti-C-X-C chemokine receptor type 5 (CXCR5) - 3931721 3931721
      Anti-C-X-C chemokine receptor type 5 (CXCR5) - Q2062044 Q2062044
      Anti-C-X-C chemokine receptor type 5 (CXCR5) -2490075 2490075
      Anti-C-X-C chemokine receptor type 5 (CXCR5) -2596513 2596513
      Anti-C-X-C chemokine receptor type 5 (CXCR5) -2621118 2621118
      Anti-C-X-C chemokine receptor type 5 (CXCR5) -2686116 2686116
      Anti-C-X-C chemokine receptor type 5 (CXCR5) Polyclonal Antibody 3023606
      Anti-C-X-C chemokine receptor type 5 -2793854 2793854

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      Catégories

      Life Science Research > Antibodies and Assays > Primary Antibodies