345749 GDF-8 Propeptide, His•Tag®, Mouse, Recombinant

345749
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      Purity
      ≥90% by SDS-PAGE

      Prix & Disponibilité

      Référence DisponibilitéConditionnement Qté Prix Quantité
      345749-25UG
      Récupération des données relatives à la disponibilité...
      Disponibilité limitéeDisponibilité limitée
      En stock 
      Interrompu(e)
      Disponible en quantités limitées
      Disponibilité à confirmer
        Pour le restant : Nous vous tiendrons informé
          Pour le restant : Nous vous tiendrons informé
          Nous vous tiendrons informé
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          Flacon en verre 25 μg
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          Description
          OverviewRecombinant, mouse growth differentiation factor-8 (GDF-8)/myostatin propeptide, consisting of amino acids 25-285, fused at the C-terminus to a His•Tag® sequence, and expressed in NS0-derived mouse myeloma cells. GDF-8 is a secreted protein that is expressed during embryonic development and in adult skeletal muscle.
          Catalogue Number345749
          Brand Family Calbiochem®
          SynonymsMyostatin Propeptide
          References
          ReferencesHill, J.J. et al. 2003. Molecular Endocrinology 17, 1144.
          Thies, R.S. et al. 2001. Growth Factors 18, 251.
          Chang, H. et al. 2002. Endocrine Reviews 23, 787.
          McPherron, A.C. et al. 1997. Nature 387, 83.
          Product Information
          FormLyophilized
          FormulationLyophilized from 0.2 µm filtered PBS, BSA.
          Quality LevelMQ100
          Applications
          ApplicationGDF-8 Propeptide, His•Tag®, Mouse, Recombinant, consists of amino acids 25-285, fused at the C-terminus to a His•Tag® sequence, and expressed in NS0-derived mouse myeloma cells.
          Biological Information
          Biological activityED₅₀ = 0.05-0.25 µg/ml (using 40 ng/ml rmGDF-8) as measured by inhibition of rmGDF-8 activity in K562 human chronic myelogenous leukemia cells. Approximately 1 µg/ml will completely inhibit GDF-8 activity in K562 cells.
          Purity≥90% by SDS-PAGE
          Physicochemical Information
          ContaminantsEndotoxin: ≤1.0 EU/µg protein
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstituyion refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          GDF-8 Propeptide, His•Tag®, Mouse, Recombinant FDS

          Titre

          Fiche de données de sécurité des matériaux (FDS) 

          GDF-8 Propeptide, His•Tag®, Mouse, Recombinant Certificats d'analyse

          TitreNuméro de lot
          345749

          Références bibliographiques

          Aperçu de la référence bibliographique
          Hill, J.J. et al. 2003. Molecular Endocrinology 17, 1144.
          Thies, R.S. et al. 2001. Growth Factors 18, 251.
          Chang, H. et al. 2002. Endocrine Reviews 23, 787.
          McPherron, A.C. et al. 1997. Nature 387, 83.
          Fiche technique

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision22-June-2011 RFH
          SynonymsMyostatin Propeptide
          DescriptionRecombinant, mouse growth differentiation factor-8 (GDF-8)/myostatin propeptide, consisting of amino acids 25-285, fused at the C-terminus to a His•Tag® sequence, and expressed in NS0-derived mouse myeloma cells. GDF-8 is a secreted protein that is expressed during embryonic development and in adult skeletal muscle.
          FormLyophilized
          FormulationLyophilized from 0.2 µm filtered PBS, BSA.
          Purity≥90% by SDS-PAGE
          ContaminantsEndotoxin: ≤1.0 EU/µg protein
          Biological activityED₅₀ = 0.05-0.25 µg/ml (using 40 ng/ml rmGDF-8) as measured by inhibition of rmGDF-8 activity in K562 human chronic myelogenous leukemia cells. Approximately 1 µg/ml will completely inhibit GDF-8 activity in K562 cells.
          SolubilityReconstitute to 50 µg/ml with sterile PBS containing ≥1% human or bovine serum albumin.
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstituyion refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesHill, J.J. et al. 2003. Molecular Endocrinology 17, 1144.
          Thies, R.S. et al. 2001. Growth Factors 18, 251.
          Chang, H. et al. 2002. Endocrine Reviews 23, 787.
          McPherron, A.C. et al. 1997. Nature 387, 83.