376817 Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem

376817
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      Empirical FormulaCAS #
      C₃H₃BrO₃ 1113-59-3

      Prix & Disponibilité

      Référence DisponibilitéConditionnement Qté Prix Quantité
      376817-100MG
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      Disponibilité limitéeDisponibilité limitée
      En stock 
      Interrompu(e)
      Disponible en quantités limitées
      Disponibilité à confirmer
        Pour le restant : Nous vous tiendrons informé
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          100 mg
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          Description
          OverviewA cell-permeable pyruvic acid derivative that acts as an inhibitor against hexokinase II-mediated glycolysis and effectively suppress tumor survival both in cultures in vitro and in mice and rats in vivo.
          Catalogue Number376817
          Brand Family Calbiochem®
          Synonyms3-BrPA, Bromopyruvate, Bromopyruvatic Acid, 3-Bromo-2-oxopropionic acid
          References
          ReferencesBujis, M., et al. 2009. Invest. New Drugs 27, 120.
          Chen, Z., et al. 2009. Biochim. Biophys. Acta. 1787, 553.
          Hulleman, E., et al. 2009. Blood. 113, 2014;
          Mathupala, S.P., et al. 2009. Semin. Cancer Biol. 19, 17.
          Pereira da Silva, A.P., et al. 2009. Biochem. J. 417, 717.
          Yun, J., et al. 2009. Science. 325, 1555.
          Zhang, X., et al. 2009. Anticancer Res. 29, 1443.
          Kim, J.S., et al. 2008. J. Bioenerg. Biomembr. 40, 607.
          Product Information
          CAS number1113-59-3
          EC number214-206-5
          FormWhite crystalline solid
          Hill FormulaC₃H₃BrO₃
          Chemical formulaC₃H₃BrO₃
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥97% by Titration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSUZ0840000
          Safety Information
          R PhraseR: 34

          Causes burns.
          S PhraseS: 26-36/37/39-45

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Corrosive
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem FDS

          Titre

          Fiche de données de sécurité des matériaux (FDS) 

          Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem Certificats d'analyse

          TitreNuméro de lot
          376817

          Références bibliographiques

          Aperçu de la référence bibliographique
          Bujis, M., et al. 2009. Invest. New Drugs 27, 120.
          Chen, Z., et al. 2009. Biochim. Biophys. Acta. 1787, 553.
          Hulleman, E., et al. 2009. Blood. 113, 2014;
          Mathupala, S.P., et al. 2009. Semin. Cancer Biol. 19, 17.
          Pereira da Silva, A.P., et al. 2009. Biochem. J. 417, 717.
          Yun, J., et al. 2009. Science. 325, 1555.
          Zhang, X., et al. 2009. Anticancer Res. 29, 1443.
          Kim, J.S., et al. 2008. J. Bioenerg. Biomembr. 40, 607.
          Fiche technique

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision02-December-2010 RFH
          Synonyms3-BrPA, Bromopyruvate, Bromopyruvatic Acid, 3-Bromo-2-oxopropionic acid
          DescriptionA cell-permeable pyruvic acid derivative that acts as an inhibitor against hexokinase II-mediated glycolysis and effectively suppress tumor survival both in cultures in vitro and in mice and rats in vivo.
          FormWhite crystalline solid
          CAS number1113-59-3
          RTECSUZ0840000
          EC number214-206-5
          Chemical formulaC₃H₃BrO₃
          Structure formulaStructure formula
          Purity≥97% by Titration
          SolubilityDMSO (100 mg/ml) or dH₂O (100 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Corrosive
          ReferencesBujis, M., et al. 2009. Invest. New Drugs 27, 120.
          Chen, Z., et al. 2009. Biochim. Biophys. Acta. 1787, 553.
          Hulleman, E., et al. 2009. Blood. 113, 2014;
          Mathupala, S.P., et al. 2009. Semin. Cancer Biol. 19, 17.
          Pereira da Silva, A.P., et al. 2009. Biochem. J. 417, 717.
          Yun, J., et al. 2009. Science. 325, 1555.
          Zhang, X., et al. 2009. Anticancer Res. 29, 1443.
          Kim, J.S., et al. 2008. J. Bioenerg. Biomembr. 40, 607.