The MOC (Mouse Oral
Cancer)
cell lines provide a syngeneic HNSCC
cancer model that can be transplanted into C57BL/6 mice. These
cell lines are important models for immune
cell infiltration applications. The MOC
lines have been utilized to compare and identify potential clinical scenarios that are applicable to
human Oral Squamous
Cell Carcinoma. The MOC1
cell line was derived from primary tumors in a C57BL/6 WT mouse and shows indolent growth compared with the aggressive, metastatic MOC2
line.
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