678937
トリス[（1-ベンジル-1H-1,2,3-トリアゾール-4-イル）メチル]アミン
97%, solid
別名:
TBTA
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この商品について
実験式（ヒル表記法）:
C30H30N10
CAS番号:
分子量:
530.63
UNSPSC Code:
12161600
PubChem Substance ID:
NACRES:
NA.22
MDL number:
製品名
トリス[（1-ベンジル-1H-1,2,3-トリアゾール-4-イル）メチル]アミン, 97%
Quality Segment
assay
97%
form
solid
reaction suitability
reagent type: ligand
reaction type: click chemistry
mp
132-143 °C
storage temp.
−20°C
SMILES string
C(N(Cc1cn(Cc2ccccc2)nn1)Cc3cn(Cc4ccccc4)nn3)c5cn(Cc6ccccc6)nn5
InChI
1S/C30H30N10/c1-4-10-25(11-5-1)16-38-22-28(31-34-38)19-37(20-29-23-39(35-32-29)17-26-12-6-2-7-13-26)21-30-24-40(36-33-30)18-27-14-8-3-9-15-27/h1-15,22-24H,16-21H2
InChI key
WKGZJBVXZWCZQC-UHFFFAOYSA-N
Application
不均一化および酸化に対してCu（I）を安定化するポリトリアゾリルアミンリガンドは、アジド-アセチレン環化付加においてその触媒効果を増強します。
hcodes
Hazard Classifications
Aquatic Chronic 4
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
資料
クリックケミストリーは、ドラッグライクな分子を合成する手法で、いくつかの実用的で信頼性の高い反応により創薬開発を加速すると期待されています。
Explore click chemistry: efficient, high-yield reactions for drug discovery, bioconjugation, and green chemistry with simple conditions and wide applications.
Laurie D Cohen et al.
PloS one, 8(5), e63191-e63191 (2013-05-10)
Chemical synapses contain multitudes of proteins, which in common with all proteins, have finite lifetimes and therefore need to be continuously replaced. Given the huge numbers of synaptic connections typical neurons form, the demand to maintain the protein contents of
Qian Wang et al.
Journal of the American Chemical Society, 125(11), 3192-3193 (2003-03-13)
The copper-catalyzed cycloaddition reaction between azides and alkynes functions efficiently in aqueous solution in the presence of a tris(triazolyl)amine ligand. The process has been employed to make rapid and reliable covalent connections to micromolar concentrations of protein decorated with either
Xiangyu Zhang et al.
Therapeutic advances in medical oncology, 12, 1758835920947976-1758835920947976 (2020-10-01)
Aspirin has recently emerged as an anticancer drug, but its therapeutic effect on lung cancer has been rarely reported, and the mechanism of action is still unclear. Long-term use of celecoxib in large doses causes serious side effects, and it