46665
プロゲステロン
VETRANAL®, analytical standard
別名:
4-プレグネン-3,20-ジオン
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この商品について
実験式（ヒル表記法）:
C21H30O2
CAS番号:
分子量:
314.46
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-350-6
Beilstein/REAXYS Number:
1915950
MDL number:
grade
analytical standard
Quality Level
product line
VETRANAL®
assay
99.5% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
128-132 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
InChI key
RJKFOVLPORLFTN-LEKSSAKUSA-N
Gene Information
human ... ESR1(2099), PGR(5241)
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
子宮内膜の成熟と分泌活性を誘導し、排卵を抑制します。
子宮内膜の成熟と分泌活性を誘導し、排卵を抑制します。プロゲステロンは乳がんの原因にかかわっています。
Other Notes
黄体で産生されるステロイドホルモンです。
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Danger
hcodes
Hazard Classifications
Carc. 2 - Lact. - Repr. 1A
保管分類
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Xiaofei Sun et al.
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Leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5) is expressed in many organs, including female reproductive organs, and is a stem cell marker in the stomach and intestinal epithelium, hair follicles, and ovarian surface epithelium. Despite ongoing studies, the definitive physiological functions
Cathrin Brisken
Nature reviews. Cancer, 13(6), 385-396 (2013-05-25)
Understanding the biology of the breast and how ovarian hormones impinge on it is key to rational new approaches in breast cancer prevention and therapy. Because of the success of selective oestrogen receptor modulators (SERMs), such as tamoxifen, and aromatase
A R Harmer et al.
The Journal of physiology, 592(3), 523-535 (2013-12-04)
Calcium cycling is integral to muscle performance during the rapid muscle contraction and relaxation of high-intensity exercise. Ca(2+) handling is altered by diabetes mellitus, but has not previously been investigated in human skeletal muscle. We investigated effects of high-intensity exercise