B0935
ベナゼプリル 塩酸塩
≥98% (HPLC), solid
別名:
(3S)-3-[[(1S)-1-(エトキシカルボニル)-3-フェニルプロピル]アミノ]-2,3,4,5-テトラヒドロ-2-オキソ-1H-1-ベンゾアゼピン-1-酢酸 塩酸塩
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この商品について
実験式（ヒル表記法）:
C24H28N2O5 · HCl
CAS番号:
分子量:
460.95
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI key
VPSRQEHTHIMDQM-FKLPMGAJSA-N
SMILES string
Cl[H].CCOC(=O)[C@H](CCc1ccccc1)N[C@H]2CCc3ccccc3N(CC(O)=O)C2=O
InChI
1S/C24H28N2O5.ClH/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28;/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28);1H/t19-,20-;/m0./s1
assay
≥98% (HPLC)
form
solid
solubility
H2O: >5 mg/mL
originator
Novartis
Quality Level
Gene Information
human ... ACE(1636)
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関連するカテゴリー
Biochem/physiol Actions
Benazepril is a long-acting angiotensin converting enzyme (ACE) inhibitor.
Features and Benefits
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
保管分類
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
B0935-BULK: + B0935-VAR: + B0935-500MG: + B0935-250MG:
jan
Yoshihiko Kanno et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 25(6), 939-943 (2002-12-18)
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disorder in humans. Hypertension is one of the major complications, and its control might affect the renal survival and disease mortality. Suitable antihypertensive agents have been discussed based
Daphne P Bicket
American family physician, 66(3), 461-468 (2002-08-17)
When first introduced in 1981, angiotensin-converting enzyme (ACE) inhibitors were indicated only for treatment of refractory hypertension. Since then, they have been shown to reduce morbidity or mortality in congestive heart failure, myocardial infarction, diabetes mellitus, chronic renal insufficiency, and
Bjoern B Burckhardt et al.
Journal of pharmaceutical and biomedical analysis, 96, 118-126 (2014-04-18)
Although serum and plasma are the biological fluids of choice for pharmacokinetic determination of drugs in adults, it is desirable to elucidate noninvasive methods which can be used for investigations in vulnerable groups such as children. If the drug properties
Nadine Bongaerts et al.
Nature communications, 13(1), 3905-3905 (2022-07-08)
Whole-cell screening for Mycobacterium tuberculosis (Mtb) inhibitors is complicated by the pathogen's slow growth and biocontainment requirements. Here we present a synthetic biology framework for assaying Mtb drug targets in engineered E. coli. We construct Target Essential Surrogate E. coli
A Salvetti et al.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 12(8), S91-S94 (1994-11-01)
SHORT- VERSUS LONG-ACTING ANGIOTENSIN CONVERTING ENZYME (ACE) INHIBITORS: Although ACE inhibitors are widely used in the treatment of hypertension, there are few data on trough:peak ratios and the data are contradictory. Part of the explanation for this lies in differences
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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