SML2217
Parecoxib sodium
≥98% (HPLC)
別名:
SC-69124, Sodium (4-(5-methyl-3-phenylisoxazol-4-yl)phenylsulfonyl)(propionyl)amide
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この商品について
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
製品名
Parecoxib sodium, ≥98% (HPLC)
InChI
1S/C19H18N2O4S.Na/c1-3-17(22)21-26(23,24)16-11-9-14(10-12-16)18-13(2)25-20-19(18)15-7-5-4-6-8-15;/h4-12H,3H2,1-2H3,(H,21,22);/q;+1/p-1
InChI key
HQPVVKXJNZEAFW-UHFFFAOYSA-M
SMILES string
CC1=C(C2=CC=C(S([N-]C(CC)=O)(=O)=O)C=C2)C(C3=CC=CC=C3)=NO1.[Na+]
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
2-8°C
関連するカテゴリー
Biochem/physiol Actions
Parecoxib sodium is a non-steroidal anti-inflammatory drug (NSAID), a cyclooxygenase-2 (COX-2) selective inhibitor. It is a water-soluble and injectable prodrug of valdecoxib.
Non-steroidal anti-inflammatory drug (NSAID), a cyclooxygenase-2 (COX-2) selective inhibitor
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Chang Liu et al.
Biochemical pharmacology, 138, 205-215 (2017-06-24)
One central factor in hepatopulmonary syndrome (HPS) pathogenesis is intravascular accumulation of activated macrophages in small pulmonary arteries. However, molecular mechanism underlying the macrophage accumulation in HPS is unknown. In this study, we aimed to explore whether elevated COX-2 induces
F Camu et al.
Acta anaesthesiologica Scandinavica, 61(1), 99-110 (2016-12-03)
This study assessed non-inferiority of parecoxib vs. combination parecoxib+propacetamol and compared the opioid-sparing effects of parecoxib, propacetamol, and parecoxib+propacetamol vs. placebo after total hip arthroplasty. In this randomized, placebo-controlled, parallel-group, non-inferiority study, patients received one of four IV treatments after
Efrain Diaz-Borjon et al.
Pain and therapy, 6(1), 61-72 (2017-03-04)
Orthopedic surgeries are among the most common and most painful surgeries performed. A multimodal analgesic approach is recommended to reduce opioid consumption, provide effective pain relief, and improve outcomes following surgery. This study examined the efficacy and opioid-sparing effects of
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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