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この商品について
実験式（ヒル表記法）:
C19H21N5O4 · HCl
CAS番号:
分子量:
419.86
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4303561
InChI key
WFXFYZULCQKPIP-UHFFFAOYSA-N
SMILES string
Cl.COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4
InChI
1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H
grade
pharmaceutical primary standard
API family
prazosin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)
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関連するカテゴリー
General description
Prazosin hydrochloride is an alpha-adrenergic blocking agent, employed as an antihypertensive drug for the treatment of high blood pressure. It lowers the blood pressure by binding to the alpha receptors thereby relaxing the blood vessels.
Application
It was used as an α1-adrenergic receptors antagonist, in a study performed to understand the influence of dopamine on uterine motility of rats in vitro.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2 - STOT RE 2 - STOT SE 3
保管分類
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
target_organs
Central nervous system
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
1554705-350MG: + 1554705-500MG:
jan
Quantitative analysis of prazosin hydrochloride in pharmaceutical formulation by prazosin potentiometric sensor based on computational investigation.
Faridbod, Farnoush, et al.
International Journal of Electrochemical Science, 5, 653-667 (2010)
Influence of dopamine on rat uterine motility in vitro.
Czerski, A., et al.
Acta Veterinaria Brno, 74.1, 9-15 (2005)
Physiologic evaluation of a new antihypertensive agent: prazosin HCl.
Koshy MC
Circulation, 55(3), 533-537 (1977)
Guyoung Kwon et al.
Life sciences, 101(1-2), 73-78 (2014-03-04)
Danshensu [3-(3,4-dihydroxyphenyl)-lactic acid], a phenylpropanoid compound isolated from Prunella vulgaris var. lilacina, is a well-known antioxidant. Although its antioxidant activity and cardioprotective effect have been reported, the pharmacological properties of danshensu in the central nervous system remain unclear. We investigated
Renny Abraham et al.
Canadian journal of physiology and pharmacology, 93(1), 13-21 (2014-11-28)
An extensive amount of research has focused on the development of new pharmacological agents to treat schizophrenia. Varying from person to person, schizophrenia is a heterogeneous disease with symptoms of positive, negative, and cognitive deficits. PRX-07034, a 5-hydroxytryptamine6 (5-HT6) receptor
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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