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1.02776

Trehalose dihydrate

EMPROVE® EXPERT, Ph. Eur., ChP, NF, JP

동의어(들):

D-(+)-Trehalose dihydrate, 1-O-alpha-D-Glucopyranosyl-alpha-D-glucopyranoside, α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C12H22O11 · 2H2O
CAS 번호:
6138-23-4
Molecular Weight:
378.33
EC Index Number:
202-739-6
UNSPSC Code:
12352201
Beilstein/REAXYS Number:
5322018
MDL number:
MFCD00071594
기술 서비스
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도움 문의

Quality Level

500

agency

ChP, JP, NF, Ph. Eur.

product line

EMPROVE® EXPERT

form

solid

feature

RNase and DNase free

mp

96.5-97.5 °C

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical
semi-solid formulation

storage temp.

no temp limit

SMILES string

[H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1

InChI key

DPVHGFAJLZWDOC-PVXXTIHASA-N

General description

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Trehalose is widely used in biomolecule formulation as a stabilizing agent.
Trehalose dihydrate Emprove® Expert is low in endotoxins and bioburden, making it the right choice for your high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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문서

Overcoming Excipient Risks and Challenges for Parenteral Formulations

This overview describes the challenges when developing parenteral formulations and strategies to overcome them and reduce the risk of production.

Use of Stabilizers and Surfactants to Prevent Protein Aggregation

This article outlines critical factors in long-term stability of proteins, and how different stabilizers protect again mechanical and thermal stress.

관련 콘텐츠

Formulation

Learn more on mAb subcutaneous or intravenous formulation, and the relevant associated products, including excipients.

Stabilizer Flyer

국제 무역 품목 번호

SKUGTIN
1.02776.100004054839467196
1.02776.901304054839467202