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この商品について
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... GDF2(2658)
Input:
sample type plasma
sample type cell culture supernatant(s)
sample type serum
sample type cell culture supernatant(s)
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 32 pg/mL
standard curve range: 32.77-8000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... GDF2(2658)
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
General description
The growth differentiation factor 2 (GDF2) gene encodes for bone morphogenic protein 9 (BMP9). GDF2, also known as BMP9, belongs to the BMP family. The GDF2 gene is mapped on the human chromosome at 10q11.22. GDF2/BMP9 protein regulates angiogenesis, modulating tumorigenesis, inhibiting hepatic glucose production, and maintaining basal forebrain cholinergic neurons. It is implicated in the pathogenesis of pulmonary arterial hypertension. Mutations in the GDF2 gene are associated with hereditary hemorrhagic telangiectasia (HHT), an autosomal dominant vascular disorder. The antibody pair provided in this kit recognizes human growth/differentiation factor 2.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
保管分類
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Please refer to KIT Component information
pdsc
Please refer to KIT Component information
prtr
Please refer to KIT Component information
fsl
Please refer to KIT Component information
ishl_indicated
Please refer to KIT Component information
ishl_notified
Please refer to KIT Component information
cart
キットコンポーネントの情報を参照してください
jan
Z Yang et al.
Science advances, 6(48) (2020-11-29)
Obesity drives the development of nonalcoholic fatty liver disease (NAFLD) characterized by hepatic steatosis. Several bone morphogenetic proteins (BMPs) except BMP9 were reported related to metabolic syndrome. This study demonstrates that liver cytokine BMP9 is decreased in the liver and
Wei Liu et al.
Genes & diseases, 7(2), 235-244 (2020-03-28)
Bone morphogenetic protein 9 (BMP9) (or GDF2) was originally identified from fetal mouse liver cDNA libraries. Emerging evidence indicates BMP9 exerts diverse and pleiotropic functions during postnatal development and in maintaining tissue homeostasis. However, the expression landscape of BMP9 signaling
Felicia Hernandez et al.
Human genome variation, 2, 15040-15040 (2015-01-01)
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder caused by mutations in ENG, ACVRL1 and SMAD4, which function in regulating the transforming growth factor beta and bone morphogenetic protein signaling pathways. Symptoms of HHT can be present in
Yongyun Li et al.
Journal of molecular and cellular cardiology, 147, 92-107 (2020-07-31)
Venous malformation (VM) is a type of vascular morphogenic defect in humans with an incidence of 1%. Although gene mutation is considered as the most common cause of VM, the pathogenesis of those without gene mutation remains to be elucidated.
Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.
Saus, et al.
Journal of Psychiatric Research, 44, 971-978 (2018)
関連コンテンツ
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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