High Quality PEG-Polystyrene Resins for the Fmoc Solid Phase Synthesis of C-terminal Peptide Acids |
NovaSyn® TGA resins are based on Tentagel, a composite of polyethylene oxide grafted on to a low cross-linked polystyrene gel-type matrix, which has been amino functionalized and derivatized with the TFA-labile 4-hydroxymethylphenoxyacetic acid linker. The 90 µm beads have a narrow size distribution, excellent pressure stability and swelling properties, and high diffusion rates, making them ideally suited for both batch or continuous flow peptide synthesis. The resin swells in a wide range of solvents, enabling coupling reactions to be carried out under a variety of conditions.