Millipore Sigma Vibrant Logo

454180 2-Methoxyestradiol - CAS 362-07-2 - Calbiochem

A natural metabolite of 17β-estradiol that is devoid of estrogenic activity.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: 2-Methoxy-3,17β-dihydroxyestra-1,3,5(10)-triene

Primary Target: Inhibits cell proliferation and angiogenesis
View Products on Sigmaaldrich.com
454180
Ver precios y disponibilidad

Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
362-07-2C₁₉H₂₆O₃

Precios y disponibilidad

Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
454180-10MG
Comprobando disponibilidad...
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

      		 Tambor de alum 10 mg
      Recuperando precio...
      No pudo obtenerse el precio
      La cantidad mínima tiene que ser múltiplo de
      Maximum Quantity is
      Al finalizar el pedido Más información
      Ahorró ()
       
      —
      Solicitar precio
      		 —
      454180-50MG
      Comprobando disponibilidad...
      —
      Disponibilidad a confirmar Disponibilidad a confirmar
      Ingrese cantidad 
      Suspendido
      Cantidades limitadas disponibles
      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
          Póngase en contacto con el Servicio de Atención al Cliente
          Contact Customer Service

          		 Tambor de alum 50 mg
          Recuperando precio...
          No pudo obtenerse el precio
          La cantidad mínima tiene que ser múltiplo de
          Maximum Quantity is
          Al finalizar el pedido Más información
          Ahorró ()
           
          —
          Solicitar precio
          		 —
          Description
          OverviewA natural metabolite of 17β-estradiol that is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Markedly inhibits the neovascularization of solid tumors and suppresses tumor growth in mice. Binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembly and function.
          Catalogue Number454180
          Brand Family Calbiochem®
          Synonyms2-Methoxy-3,17β-dihydroxyestra-1,3,5(10)-triene
          References
          ReferencesAizu-Yokata, E., et al. 1995. Cancer Res. 55, 1863.
          Cushman, M., et al. 1995. J. Med. Chem. 38, 2041.
          D’Amato, R.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3964.
          Forsis, T., et al. 1994. Nature 368, 237.
          Product Information
          CAS number362-07-2
          ATP CompetitiveN
          FormWhite crystalline solid
          Hill FormulaC₁₉H₂₆O₃
          Chemical formulaC₁₉H₂₆O₃
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetInhibits cell proliferation and angiogenesis
          Purity≥90% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 23/24/25-36/37/38

          Toxic by inhalation, in contact with skin and if swallowed.
          Irritating to eyes, respiratory system and skin.
          S PhraseS: 22-26-36/37/39-45

          Do not breathe dust.
          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Toxic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Número de referencia GTIN
          454180-10MG 04055977204728
          454180-50MG 04055977204735

          Documentation

          Licencias necesarias

          Título
          CARTA DE USO GENERAL 2016
          PRODUCTO REGULADO POR LA SAGARPA
          PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

          2-Methoxyestradiol - CAS 362-07-2 - Calbiochem Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          2-Methoxyestradiol - CAS 362-07-2 - Calbiochem Certificados de análisis

          CargoNúmero de lote
          454180

          Referencias bibliográficas

          Visión general referencias
          Aizu-Yokata, E., et al. 1995. Cancer Res. 55, 1863.
          Cushman, M., et al. 1995. J. Med. Chem. 38, 2041.
          D’Amato, R.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3964.
          Forsis, T., et al. 1994. Nature 368, 237.
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision15-May-2008 RFH
          Synonyms2-Methoxy-3,17β-dihydroxyestra-1,3,5(10)-triene
          DescriptionA natural metabolite of 17β-estradiol that is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Markedly inhibits neovascularization of solid tumors and suppresses tumor growth in mice. Binds to the colchicine binding site of tubulin and has been suggested to function as a natural regulator of microtubule assembly and function.
          FormWhite crystalline solid
          CAS number362-07-2
          Chemical formulaC₁₉H₂₆O₃
          Structure formulaStructure formula
          Purity≥90% by HPLC
          SolubilityDMSO or Ethanol
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Toxicity Toxic
          ReferencesAizu-Yokata, E., et al. 1995. Cancer Res. 55, 1863.
          Cushman, M., et al. 1995. J. Med. Chem. 38, 2041.
          D’Amato, R.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3964.
          Forsis, T., et al. 1994. Nature 368, 237.