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ABT334 Anti-TSLP receptor Antibody

Detect TLSP Receptor using this rabbit polyclonal antibody, Anti-TSLP receptor Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.

Anti-TSLP receptor Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Signaling Research Sub-Category: Cytokines & Cytokine Receptors Gene Symbol: CRLF2 UniProt Number: Q9HC73
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ABT334
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IH(P), IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT334
      DescriptionAnti-TSLP receptor Antibody
      Alternate Names
      • TSLP Receptor Antibody
      • TSLP Receptor
      • Thymic stromal lymphopoietin receptor
      • CRL2
      • ILXR
      • TSLPR
      • Cytokine receptor-like factor 2
      • Cytokine receptor-like 2
      • IL-XR
      Background InformationThymic stromal lymphopoietin (TSLP) receptor is a member of the Type I cytokine receptor family (type 5 subfamily). TSLP has been shown to play an important role in dendritic cell maturation and activation. Additionally, TSLP receptor is involved in the positive selection of regulatory T cells, induction of CD4+ T cell-mediated allergic reaction and maintenance of peripheral CD4+ T cell homeostasis. Furthermore, TSLP receptor is implicated in the development of the hematopoietic system. TSLP receptor forms a functional complex with TSLP receptor and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. TSLP receptor is primarily expressed in dendrites and monocytes. Additionally, it is expressed in heart, skeletal muscle, kidney and adult and fetal liver; and weakly expressed in T-cells.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human liver tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect TLSP Receptor using this rabbit polyclonal antibody, Anti-TSLP receptor Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      • Immunofluorescence
      Application NotesImmunohistochemistry Analysis: 5 µg/mL from a representative lot detected TSLP receptor in human liver tissue.

      Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TSLP receptor in human liver cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human TSLP receptor.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • CRLF2
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~53 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~27 kDa and ~42 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human liver tissue lysate.

      Western Blotting Analysis: 2 µg/mL of this antibody detected TSLP receptor in 15 µg of human liver tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      ABT334 04053252905568