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Tokyo, Japan
ADC | Merck

2018 ADC Symposium

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Tuesday, October 30, 2018

You are invited to participate in Merck’s 2018 ADC Symposium to learn, share and discuss today’s advancements with your peers and subject matter experts of the industry.

This one-day event will include:

Merck M Lab™
  • Industry experts presenting advancements in ADC / bioconjugation development and drug-linker technologies, like activated PEGs and HPAPIs
  • Innovative ADC processing showcasing the latest technology at our MLab™ collaboration center
  • Opportunities to network with experts and peers during refreshment breaks and lunch.

Preliminary Agenda*

 
9:45 AMRegistration & Morning Coffee
 
10:20 AMWelcome & Introduction
 Robert Guagliardo, VP & Head of Actives & Formulation Commercial, Merck
 
 Advancing Development of ADCs & Bioconjugation
 
10:30 AMHydrophilic and Site-Specific Antibody- Drug Conjugates to Treat Tumors
 Dr. Ping-Fu Cheng, ITRI (Taiwan)
 
11:00 AMABL201: an anti-BCMA antibody-drug conjugate with NTERM conjugation
 Dr. Jinwon Jung, ABL Bio Inc.
 
11:30 AMBreak
 
11:45 AMCreating Next Generation ADCs with Industry Leading DAR Precision and Plasma Stability
 Dr. Jeiwook Chae, LegoChem Biosciences Inc.
 
12:15 PMADCs with high DAR, high targeting valence, and product homogeneity
 Dr. Tse Wen Chang, Immunwork Inc.
 
12:45 PMLunch Break
 
 Technology Insights & Processing Solutions
 
1:30 PMEvaluation of a Novel Single-use TFF Capsule
 Yoshiaki Ogawa, Merck
 
1:45 PMSingle use Equipment for ADC Processing: From Lab Sale to GMP Production
 Siyi Liao, Merck
Dr. Gang Yao, Merck
 
2:15 PMDemonstration of Solvent Compatibility and Extractables Profile for Use of Mobius® Assemblies in ADC Processing
 Dr. Takao Ito, Merck
 
2:30 PMMLab™ Collaboration Center rotating group tours, Q&A time with experts, poster exhibition & coffee break
 
3:45 PMTrends in Drug-linker Technologies: novel HPAPIs, Discrete & Activated PEGs
 Dr. Matthias Joehnck, Merck
 
4:15 PMTackling the Complex ADC Supply Chain: Best Practice Approach and Integrated Program Management Case Study
 Latashuia Browning, Merck
 
4:45 PMWrap-up and closing remarks
 Isao Hatano, Head of Process Solutions Japan, Merck
 
5:00 PMPost-event reception
 Grand Nikko Daiba, 29F (Akane), 2-6-1, Daiba, Minato-ku, Tokyo 135-8701, Japan
 
8:00 PMEnd
 

The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the US and Canada.

* This agenda is subject to change and will be updated during the course of the next months. The event is free; registration is mandatory and space is limited to 40 attendees. Attendance to the “2018 ADC Symposium” is limited and available to pharma/biopharma manufacturers only. The offer does not extend to any company that provides products or services to the pharma/biopharma industry. Merck reserves the right to revoke or refuse participation at any times.

Refreshments are provided courtesy of Merck. Travel costs, hotel accommodations and any other costs incurred are at the expense of the attendees.

Venue:  MLab™ Collaboration Center, Tokyo
Merck Burlington, MA

The Symposium will take place at our MLab™ Collaboration Center in Tokyo Japan:

Divercity Tokyo office tower 20F
Aomi, 1-1-20
Koto-ku
Tokyo 〒135-0064
Tel: +81-3-6759-8560

Learn about our M Lab™ Collaboration Centers

Abstracts of Our Speakers
Hydrophilic and Site-Specific Antibody- Drug Conjugates to Treat Tumors

Cheng PingFu, Ph.D.
Principal Investigator of site-specific ADC project

View Abstract
ABL201: an Anti-BCMA Antibody-drug Conjugate with NTERM Conjugation

Jinwon Jung, Ph.D.
Principal Scientist, ABL Bio Inc.

View Abstract
Creating Next Generation ADCs with Industry Leading DAR Precision and Plasma Stability

Jeiwook Chae, Ph.D.
Chief Business Development Officer, LegoChem Biosciences, Inc.

View Abstract
ADCs with high DAR, high targeting valence, and product homogeneity

Tse-Wen Chang, Ph.D.
CEO, Immunwork, Inc.

View Abstract
Evaluation of a Novel Single-use TFF Capsule

Yoshiaki Ogawa
Technology Manager for Tangential Flow Filtration (TFF), Merck

View Abstract
Implementation of a Complete Single-use Production Process & Scale-up Case Study

Gang Yao, Ph.D.
Principal Scientist, Process and Analytical Development, Merck

View Abstract
Mobius® Technology Supporting ADC Processing

Siyi Liao
System Process Engineer, Manufacturing Sciences And Technology, Merck

View Abstract
Demonstration of Solvent Compatibility and Extractables Profile for Use of Mobius® Assemblies in ADC Processing

Takao Ito, Ph.D.
Head of Manufacturing Sciences & Technology (MSAT) Japan and Korea, Merck

View Abstract
Trends in Drug-linker Technologies: HPAPIs & activated PEGs

Matthias Jöhnck, Ph.D.
Senior Director, Head of Actives & Formulation, Research & Development, Merck

View Abstract
Tackling the Complex ADC Supply Chain: Best Practice Approach and Integrated Program Management Case Study

Latashuia Browning
Sr. Director & Head of Sales, Americas, Actives & Formulation, Merck

View Abstract