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ABD75 Anti-THAP11 (Ronin) Antibody

This Anti-THAP11 (Ronin) Antibody is validated for use in Western Blotting, IHC for the detection of THAP11 (Ronin).

Anti-THAP11 (Ronin) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: THAP11 UniProt Number: Q96EK4
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ABD75
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABD75
      DescriptionAnti-THAP11 (Ronin) Antibody
      Alternate Names
      • THAP domain-containing protein 11
      Background InformationTHAP11 (Ronin) is a transcriptional repressor which is predominantly expressed in embryonic stem (ES) cells. It contains a THAP-type zinc finger domain which is characteristic of the THAP 11 family members. In ES cells, THAP11 interacts with the transcriptional co-regulator HCF-1, to recruit chromatin-modifying proteins such as members of the polycomb family of proteins, to induce gene repression. THAP11 targets genes involved in metabolism, transcriptional initiation, and messenger RNA splicing. It plays an important role in maintaining the pluripotent state of ES cells.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Mouse heart tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-THAP11 (Ronin) Antibody is validated for use in Western Blotting, IHC for the detection of THAP11 (Ronin).
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blot Analysis: 1 µg/mL from a representative lot detected THAP11 on 10 µg of mouse liver tissue lysate.

      Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected THAP11 in mouse cardiac muscle and mouse liver tissues.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human THAP11.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Mouse
      Species Reactivity NoteDemonstrated to react with Mouse. Predicted to react with Rat based on 100% sequence homology. Predicted to react with Human based on immunogen design.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • THAP11
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~48 kDa observed. Uncharacterized bands appear at ~20-25 kDa in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in mouse heart tissue lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected THAP11 on 10 µg of mouse heart tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABD75 04053252648823

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies