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852110 Fmoc-(Dmb)Gly-OH

Fmoc-(Dmb)Gly-OH Novabiochem®. CAS 166881-42-1, molar mass 447.48 g/mol.

Fmoc-(Dmb)Gly-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 166881-42-1 Molar Mass: 447.48 g/mol Hill Formula: C₂₆H₂₅NO₆
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852110
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
166881-42-1C₂₆H₂₅NO₆447.48 g/mol

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          Description
          Catalogue Number852110
          Replaces04-12-1268
          Brand Family Novabiochem®
          Alternate Names
          • N-α-Fmoc-N-α-(2, 4-dimethoxybenzyl)-glycine
          Background InformationFmoc-(Dmb)Gly-OH is an excellent reagent for enhancing synthetic efficiency of glycine-containing peptides.

          Like the analogous Hmb derivative Fmoc-(FmocHmb)Gly-OH, the use of this derivative prevents aggregation during chain assemby, thereby leading to faster and more predictable acylation and deprotection reactions. Furthermore, it can prevent aspartimide formation when used to introduce a Gly immediately before an Asp residue and help promote cyclization of Gly-containing peptides [1].

          The analogous (Tmob)Gly derivative has been used by Bayer and colleagues to prepare a 64-residue transmembrane peptide in remarkable purity [2].

          The product number for this product was previously 04-12-1268.

          To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
          References
          Product Information
          CAS number166881-42-1
          Hill FormulaC₂₆H₂₅NO₆
          Molar Mass447.48 g/mol
          Structure formula ImageStructure formula Image
          Quality LevelMQ200
          Applications
          ApplicationFmoc-(Dmb)Gly-OH Novabiochem®. CAS 166881-42-1, molar mass 447.48 g/mol.
          Biological Information
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Storage class10 - 13 Other liquids and solids
          WGKWGK 3 highly hazardous to water
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at -15°C to -25°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Color (visual)white to slight yellow to beige
          Appearance of substance (visual)powder
          Identity (IR)passes test
          Purity (TLC(157B))≥ 98 %
          Assay (HPLC, area%)≥ 99.0 % (a/a)
          Solubility (1 mmole in 2 ml DMF)passes test
          Assay (acidimetric)≥ 94.0 %
          Water (K. F.)≤ 1.00 %
          For TLC-Systems see our General Catalog
          Global Trade Item Number
          Catalogue Number GTIN
          8521100001 04027269089757
          8521100005 04027269089764

          Documentation

          Fmoc-(Dmb)Gly-OH SDS

          Title

          Safety Data Sheet (SDS) 

          Citations

          Title
          • [1] M. El Haddadi, et al. (2000) J. Pept. Sci., 6, 560 (2000) J. Pept. Sci., 6, 560.
          • [2] K. Jauch, et al. in "Peptides 1996: Proc. 24th European Peptide Symposium", R. Ramage and R. Epton (Eds), Mayflower Scientific Ltd., 1996, pp 497.