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852082 Fmoc-Lys(ivDde)-OH

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
204777-78-6C₃₄H₄₂N₂O₆574.71 g/mol

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      8520820005
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          Description
          Catalogue Number852082
          Replaces04-12-1193
          Brand Family Novabiochem®
          Alternate Names
          • N-α-Fmoc-N-ε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-lysine
          Background InformationThis orthogonally-protected lysine derivative is based on the hindered Dde variant ivDde. It has very similar chemical properties to Fmoc-Lys(Dde)-OH, except that the side-chain ivDde group is considerably more stable to piperidine than Dde, and is less prone to migrate from protected to unprotected lysine side-chains [1].

          When removing ivDde in the presence of allyl based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [2].

          The product number for this product was previously 04-12-1193.

          To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
          References
          Product Information
          CAS number204777-78-6
          Hill FormulaC₃₄H₄₂N₂O₆
          Molar Mass574.71 g/mol
          Structure formula ImageStructure formula Image
          Quality LevelMQ200
          Applications
          ApplicationFmoc-Lys(ivDde)-OH Novabiochem®. CAS 204777-78-6, molar mass 574.72 g/mol.
          Biological Information
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Storage class10 - 13 Other liquids and solids
          WGKWGK 3 highly hazardous to water
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at -10°C to -25°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Color (visual)white to slightly yellow to beige
          Appearance of substance (visual)powder
          Identity (IR)passes test
          Enantiomeric purity≥ 99.5 % (a/a)
          Purity (TLC(157B))≥ 97 %
          Purity (TLC(CMA2))≥ 97 %
          Assay (HPLC, area%)≥ 99.0 % (a/a)
          Solubility (1 mmole in 2 ml DMF)clearly soluble
          Assay (acidimetric)≥ 85.0 %
          Water (K. F.)≤ 1.00 %
          For TLC-Systems see our General Catalog
          Global Trade Item Number
          Catalogue Number GTIN
          8520820001 04027269088675
          8520820005 04027269088682

          Documentation

          Fmoc-Lys(ivDde)-OH SDS

          Title

          Safety Data Sheet (SDS) 

          Citations

          Title
          • [1] S. R. Chhabra, et al. (1998) Tetrahedron Lett., 39, 1603.
          • [2] B. Rohwedder, et al. (1998) Tetrahedron Lett., 39, 1175.
          • [3] V. Wittmann & S. Seeberger (2000) Angew. Chem. Int. Ed. Engl., 39, 4348.