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851013 HATU

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
148893-10-1C₁₀H₁₅N₆O * F₆P380.23 g/mol

Pricing & Availability

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8510130025
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      8510130100
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          Plastic bottle 100 g
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          Description
          Catalogue Number851013
          Replaces01-62-0041
          Brand Family Novabiochem®
          Background InformationA highly efficient coupling reagent for solid and solution phase peptide synthesis. In comparative studies HATU has been found to give better coupling yields with less enantiomerization that HBTU, TBTU or PyBOP® [1-3]. It is particularly effective at coupling to N-alkyl amines where other coupling reagents give poor yields and is the preferred reagent for loading resins bearing secondary amino groups.

          The product number for this product was previously 01-62-0041.

          To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
          References
          Product Information
          CAS number148893-10-1
          Hill FormulaC₁₀H₁₅N₆O * F₆P
          Molar Mass380.23 g/mol
          HS Code2933 99 99
          Structure formula ImageStructure formula Image
          Quality LevelMQ300
          Applications
          ApplicationHATU Novabiochem®. CAS 148893-10-1, molar mass 380.23 g/mol.
          Biological Information
          Physicochemical Information
          Melting Point186 °C decomposes
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Statement(s)H317: May cause an allergic skin reaction.
          H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
          EUH044: Risk of explosion if heated under confinement.
          Precautionary Statement(s)P261: Avoid breathing dust.
          P272: Contaminated work clothing should not be allowed out of the workplace.
          P280: Wear protective gloves.
          P284: Wear respiratory protection.
          P302 + P352: IF ON SKIN: Wash with plenty of water.
          P333 + P313: If skin irritation or rash occurs: Get medical advice/ attention.
          Signal WordDanger
          Storage class4.1B Flammable solid hazardous materials
          WGKWGK 3 highly hazardous to water
          Safety Information
          Categories of dangersensitizing
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +2°C to +8°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 1325 , 4.1, II
          Declaration (transport by air) IATA-DGRUN 1325 , 4.1, II
          Declaration (transport by sea) IMDG-CodeUN 1325 , 4.1, II
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          8510130025 04027269081287
          8510130100 04027269566227

          Documentation

          HATU SDS

          Title

          Safety Data Sheet (SDS) 

          Citations

          Title
          • [1] L. A. Carpino (1993) J. Am. Chem. Soc., 115, 4397.
          • [2] F. Albericio, et al. (1998) J. Org. Chem., 63, 9678.
          • [3] J. A. Carpino, et al., in "Innovation & Perspectives in Solid Phase Synthesis, 3rd International Symposium", R. Epton (Ed.), Mayflower Worldwide Ltd., 1994, pp. 95.