Millipore Sigma Vibrant Logo

SCM075 ROCK Inhibitor (Y-27632)

The ROCK Inhibitor (Y-27632) is available in a 5 mg format & has been optimized & validated for cell culture & Neuroscience applications.

ROCK Inhibitor (Y-27632) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Cell Culture, Neuroscience
View Products on Sigmaaldrich.com
SCM075
5 mg  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Fulfillment and delivery delayed Fulfillment and delivery delayed
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

       

      Contact Customer Service

      Overview

      Replacement Information

      Key Spec Table

      Key Applications
      CULT, Neuroscience
      Description
      Catalogue NumberSCM075
      DescriptionROCK Inhibitor (Y-27632)
      Background InformationROCK Inhibitor (Y-27632) is a selective, ATP-competitive inhibitor of Rho-associated protein kinase (ROCK) including p160Rock (Ki=140nM) and Rock-II. Also acts as a potent inhibitor of agonist-induced Ca2+ sensitization of myosin phosphorylation and smooth muscle contraction. One-hour treatment with 10uM Y-27632 blocks apoptosis of dissociated cultured human embryonic stem cells (hESCs), increases survival and cloning efficiency of hESCs without affecting their pluripotency1. Recently, some reports showed that the application of Y-27632 and Accutase (Cat. No. SCR005), a formulated mixture of digestive enzymes, enhances the post-thaw survival rate of single hESCs using conventional slow freezing and rapid thawing methods
      References
      Product Information
      HS Code2933 39 99
      Quality LevelMQ100
      Applications
      ApplicationThe ROCK Inhibitor (Y-27632) is available in a 5 mg format & has been optimized & validated for cell culture & Neuroscience applications.
      Key Applications
      • Cell Culture
      • Neuroscience
      Biological Information
      Media FormLiquid
      Molecular Weight320.26 g/mol
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsBefore Reconstitution: Maintain at -20ºC, protected from light for 2 years. After Reconstitution: 1 year at -20ºC, protected from light
      Packaging Information
      Material Size5 mg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      SCM075 04053252374654

      Documentation

      ROCK Inhibitor (Y-27632) SDS

      Title

      Safety Data Sheet (SDS) 

      ROCK Inhibitor (Y-27632) Certificates of Analysis

      TitleLot Number
      ROCK Inhibitor (Y-27632) 5 mg 2975574
      ROCK Inhibitor (Y-27632) 5 mg 2934776
      ROCK Inhibitor (Y-27632) 5 mg 3091588
      ROCK Inhibitor (Y-27632) 5 mg 2829752
      ROCK Inhibitor (Y-27632) 5 mg - 2427507 2427507
      ROCK Inhibitor (Y-27632) 5 mg - 2053029 2053029
      ROCK Inhibitor (Y-27632) 5 mg - 2196069 2196069
      ROCK Inhibitor (Y-27632) 5 mg - 2325726 2325726
      ROCK Inhibitor (Y-27632) 5 mg - 3236527 3236527
      ROCK Inhibitor (Y-27632) 5 mg - 3287863 3287863
      Show more

      Brochure

      Title
      Human Stem Cell Systems

      Related Products & Applications

      Accessories

      Catalogue Number Description  
      SCR005 Accutase cell detachment solution Show Pricing & Availability
      SCR006 Accumax Cell Counting Solution in DPBS Sterile-filtered Cell Culture Tested Show Pricing & Availability
      SCR502 Human, iPS Selection Kit Show Pricing & Availability
      SCR530 STEMCCA Constitutive Polycistronic (OKSM) Lentivirus Reprogramming Kit Show Pricing & Availability
      SCR531 STEMCCA Cre-Excisable Constitutive Polycistronic (OKSM) Lentivirus Reprogramming Kit Show Pricing & Availability

      Categories

      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Media Supplements