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AB1565 | Anti-Vasopressin Antibody

AB1565
100 µL  
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      Replacement Information

      Ofertas especiales

      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R, Rb, Sh ICC, IH(P), RIA, WB Rb Serum Polyclonal Antibody
      Description
      Catalogue NumberAB1565
      ReplacesAB937
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Vasopressin Antibody
      References
      Product Information
      FormatSerum
      Control
      • Hypothalamus
      PresentationNeat rabbit antisera. Liquid, with 0.1% sodium azide.
      Applications
      ApplicationAnti-Vasopressin Antibody detects level of Vasopressin & has been published & validated for use in IC, IH(P), RIA & WB.
      Key Applications
      • Immunocytochemistry
      • Immunohistochemistry (Paraffin)
      • Radioimmunoassay
      • Western Blotting
      Application NotesImmunohistochemistry: 1:5,000-1:10,000 (18-24 hour incubation) on formalin, Bouin's or Zamboni's fixed tissue. Will react on paraffin embedded tissue.

      Immunocytochemistry: 1:1,000-1:200,000 (18-24 hour incubation) on fetal rat neurons.

      Immunoblotting: 1:1,000

      RIA: 1:30,000-1:750,000. Sensitivity of < 1 pg/mL.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenArginine vasopressin (Sigma) conjugated to thyroglobulin.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Vasopressin. Less than 1% cross-reactivity with oxytocin.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      • Rabbit
      • Sheep
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin II and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin II, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI).
      Gene Symbol
      • AVP
      • AVP-NPII
      • VP
      • AVRP
      • ARVP
      • ADH
      Purification MethodUnpurified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01185 # Vasopressin has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels.
      SIZE: 164 amino acids; 17325 Da
      SUBCELLULAR LOCATION: Secreted.
      DISEASE: SwissProt: P01185 # Defects in AVP are the cause of autosomal dominant neurohypophyseal diabetes insipidus (ADNDI) [MIM:125700]. ADNDI is characterized by persistent thirst, polydipsia and polyuria. The disease is transmitted in an autosomal dominant mode and appears to be largely if not completely penetrant. & Defects in AVP are the cause of autosomal recessive neurohypophyseal diabetes insipidus (ARNDI) [MIM:125700]. ARNDI is characterized by persistent thirst, polydipsia and polyuria. Most mutations are hypothesized to trigger neurodegeneration via disruption of preproAVP-NPII processing.
      SIMILARITY: SwissProt: P01185 ## Belongs to the vasopressin/oxytocin family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Certificados de análisis

      CargoNúmero de lote
      RABBIT ANTI-VASOPRESSIN 2477836
      RABBIT ANTI-VASOPRESSIN POLYCLONAL ANTIBODY - 2118000 2118000
      RABBIT ANTI-VASOPRESSIN POLYCLONAL ANTIBODY - 2428472 2428472
      RABBIT ANTI-VASOPRESSIN -2607294 2607294
      RABBIT ANTI-VASOPRESSIN -2689051 2689051
      RABBIT ANTI-VASOPRESSIN -2707875 2707875
      RABBIT ANTI-VASOPRESSIN -2772779 2772779
      RABBIT ANTI-VASOPRESSIN -2812039 2812039
      RABBIT ANTI-VASOPRESSIN -2829982 2829982
      RABBIT ANTI-VASOPRESSIN POLYCLONAL ANTIBODY - 2191941 2191941
      RABBIT ANTI-VASOPRESSIN POLYCLONAL ANTIBODY - 2365946 2365946
      RABBIT ANTI-VASOPRESSIN POLYCLONAL ANTIBODY -2502889 2502889

      Referencias bibliográficas | 22 Disponible | Ver todas las referencias

      Visión general referenciasPub Med ID
      An ultrastructural analysis of the effects of ethanol self-administration on the hypothalamic paraventricular nucleus in rhesus macaques.
      Jimenez, VA; Helms, CM; Cornea, A; Meshul, CK; Grant, KA
      Frontiers in cellular neuroscience 9 260 2015

      Mostrar resumen
      26236193 26236193
      Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer's disease.
      Lim, AS; Ellison, BA; Wang, JL; Yu, L; Schneider, JA; Buchman, AS; Bennett, DA; Saper, CB
      Brain : a journal of neurology 137 2847-61 2014

      Mostrar resumen
      25142380 25142380
      Syndrome of inappropriate antidiuretic hormone secretion in patients with olfactory neuroblastoma.
      Stacey T Gray,Eric H Holbrook,Mohammed H Najm,Peter M Sadow,William T Curry,Derrick T Lin
      Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 147 2012

      Mostrar resumen
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      Early life stress disrupts peripubertal development of aggression in male mice.
      Tsuda MC, Yamaguchi N, Ogawa S
      Neuroreport 22 259-63. 2011

      Mostrar resumen
      21403582 21403582
      Novel FGF8 mutations associated with recessive holoprosencephaly, craniofacial defects, and hypothalamo-pituitary dysfunction.
      Mark J McCabe,Carles Gaston-Massuet,Vaitsa Tziaferi,Louise C Gregory,Kyriaki S Alatzoglou,Massimo Signore,Eduardo Puelles,Dianne Gerrelli,I Sadaf Farooqi,Jamal Raza,Joanna Walker,Scott I Kavanaugh,Pei-San Tsai,Nelly Pitteloud,Juan-Pedro Martinez-Barbera,Mehul T Dattani
      The Journal of clinical endocrinology and metabolism 96 2011

      Mostrar resumen
      21832120 21832120
      A role of the LIM-homeobox gene Lhx2 in the regulation of pituitary development.
      Zhao Y, Mailloux CM, Hermesz E, Palkóvits M, Westphal H
      Developmental biology 337 313-23 2010

      Mostrar resumen Artículo Texto completo
      19900438 19900438
      Functional hypothalamic amenorrhea due to increased CRH tone in melanocortin receptor 2-deficient mice.
      Matsuwaki, T; Nishihara, M; Sato, T; Yoda, T; Iwakura, Y; Chida, D
      Endocrinology 151 5489-96 2010

      Mostrar resumen
      20881239 20881239
      Different antipsychotics elicit different effects on magnocellular oxytocinergic and vasopressinergic neurons as revealed by Fos immunohistochemistry.
      A Kiss, J Bundzikova, Z Pirnik, JD Mikkelsen
      Journal of neuroscience research 88 677-85 2010

      Mostrar resumen
      19774673 19774673
      Juvenile social experience regulates central neuropeptides relevant to emotional and social behaviors.
      K Tanaka, Y Osako, K Yuri
      Neuroscience 166 1036-1042 2010

      Mostrar resumen
      20096332 20096332
      Vasopressin synthesis by the magnocellular neurons is different in the supraoptic nucleus and in the paraventricular nucleus in human and experimental septic shock.
      Sonneville R, Guidoux C, Barrett L, Viltart O, Mattot V, Polito A, Siami S, de la Grandmaison GL, Blanchard A, Singer M, Annane D, Gray F, Brouland JP, Sharshar T
      Brain Pathol 20 613-22. Epub 2009 Nov 9. 2010

      Mostrar resumen
      20015289 20015289

      Ficha técnica

      Cargo
      Anti-Vasopressin - Data Sheet