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EZHFGF21-19K | Human FGF-21 ELISA Kit

EZHFGF21-19K
96-well strip plate  
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      Descripción

      Replacement Information

      Tabla espec. clave

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      FGF-21 H ELISA Fluorescent, Colorimetric
      Description
      Catalogue NumberEZHFGF21-19K
      DescriptionHuman FGF-21 ELISA Kit
      Background InformationRecent studies have demonstrated that fibroblast growth factor 21 (FGF-21), a liver derived protein, is able to increase glucose uptake, as well as lower plasma triglyceride levels in an insulin-independent manner. FGF-21 suppresses glucagon release, thereby increasing insulin sensitivity, and reduces the amount of insulin production required by pancreatic β-cells. Unlike insulin, which works in a rapid, hormone-like manner, FGF-21 activity requires several hours, indicating changes in gene expression. While insulin functions through GLUT4 translocation, FGF-21 has been shown to act primarily through the upregulation of adipocyte GLUT1, a transporter that allows glucose to move from the blood into cells even in the absence of insulin. In addition, no significant weight gain was observed when FGF-21 was injected into animals, and mice that had been genetically engineered to overexpress FGF-21 weighed less and had less adipose tissue than the normal controls.
      References
      Product Information
      Detection methodFluorescent Colorimetric
      Precision, %
      • Intra-assay: < 6%
      • Inter-assay: < 9%
      Applications
      ApplicationThis Human FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research.
      Key Applications
      • ELISA
      Application NotesThis is a 3-hour assay requiring 50 μL of sample.
      Biological Information
      SpecificityNo significant cross-reactivity to the cytokines and metabolic hormones tested was observed.
      Species Reactivity
      • Human
      Analytes Available
      • FGF-21
      Accuracy
      • 83 – 99%
      Physicochemical Information
      Linearity of DilutionPlease contact Technical Service for this information
      Standard Curve Range
      • 31.3– 2000 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well strip plate
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Protocols

      Title
      Protocol: Human Fibroblast Growth Factor-21 (FGF-21) ELISA KIT - 96-Well Plate

      Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Folleto

      Cargo
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      ELISAs, RIAs & GyroMark HT Assays
      Immunoassay and Multiplex Kits: Analyte Quarterly Vol. 2, 2016
      Protein Detection Platform and Services Brochure

      Licencias necesarias e Información técnica

      Cargo
      96 well Template 2 Up
      96 well Template Single
      Quality Control Range: Human Fibroblast Growth Factor-21 (FGF-21) ELISA Kit

      Ficha técnica

      Cargo
      Full Service Custom-built Assays

      Póster

      Cargo
      Multiplex Assays of Fifteen Human Complement Factors

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      Categorías

      Life Science Research > Protein Detection and Quantification > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits
      Life Science Research > Antibodies and Assays > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits