A part of Merck

Módulos de microfiltración Prostak

Membrane-based separations device in Prostak Tangential Flow Filter (TFF) Systems.



Información para pedidos


    Licencias necesarias e Información técnica

    Clarification and Recovery of Recombinant Proteins using a Cascade Tangential Flow Filtration (TFF) System

    Preguntas frecuentes

    What is Normalized Water Permeability? NWP is a measure of the ability of pure water to pass through the filter membrane. NWP is a property of the TFF system and is contributed to by the membrane as well as the feed and permeate flow paths in the filter.
    How is NWP measured? NWP is measured by filtering pure water throught he system at controlled cross flow, Trans Membrane Pressure and temperature. The filtrate flow rate is measured. The flow rate is normalized to the membrane area, TMP and temperature.

    Please refer to the operator's manual or contact Techical Service for further questions regarding the calculation of NWP.
    How does NWP aid in effective cleaning procedure development? Fouling and polarization leave residues on the membrane that can reduce filter permeability. Effective cleaning removes these residues, restoring the permeability of the membrane. Ideally, NWP after cleaning should equal NWP before use although there can be variation up to +/-15% due to membrane compaction under pressure and measurement error.

    NWP validates the ability of cleaning to restore filtration rate of a system.