PKC
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539573 Sigma-AldrichPKC Inhibitor Set - Calbiochem
The PKC Inhibitor Set controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
07-330 Sigma-AldrichAnti-Partitioning-defective 3 Antibody
Anti-PAR-3, Cat. No. 07-330 rabbit polyclonal antibody that detects PAR-3 and is tested for use in Immunocytochemistry and Western Blotting.
557520 Sigma-AldrichRo-31-8220 - CAS 138489-18-6 - Calbiochem
A cell-permeable, reversible, competitive, and selective inhibitor of protein kinase C (PKC; IC₅₀ = 10 nM) over CaM kinase II (IC₅₀ = 17 µM) and protein kinase A (IC₅₀ = 900 nM).
203290 Sigma-AldrichBisindolylmaleimide I - CAS 133052-90-1 - Calbiochem
Bisindolylmaleimide I, CAS 133052-90-1, is a cell-permeable, highly selective, reversible inhibitor of protein kinase C (IC50 = 10 nM). Acts on the ATP-binding site of PKC.
365251 Sigma-AldrichGö 6983 - CAS 133053-19-7 - Calbiochem
Gö 6983, CAS 133053-19-7, is a potent, cell-permeable, reversible, and ATP-competitive inhibitor of several PKC isozymes (IC50 = 7 nM for PKCα & β; 6 nM for PKCγ; 10 nM for PKCδ; & 60 nM for PKCζ).
524400 Sigma-AldrichPhorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem
Phorbol-12-myristate-13-acetate, CAS 16561-29-8, acts as an extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro at nM concentrations.
527948 Sigma-AldrichPiceatannol - CAS 10083-24-6 - Calbiochem
A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC₅₀ = 3 µM), PKC (IC₅₀ = 8 µM), MLCK (IC₅₀ = 12 µM).
365250 Sigma-AldrichGö 6976 - CAS 136194-77-9 - Calbiochem
Gö 6976, CAS 136194-77-9, is a cell-permeable, reversible, and ATP-competitive inhibitor of PKC (IC₅₀ = 7.9 nM for rat brain). Exhibits selectively for PKCα (IC₅₀ = 2.3 nM) and βI (IC₅₀ = 6.2 nM).
569397 Sigma-AldrichStaurosporine, Streptomyces sp.
Staurosporine, CAS 62996-74-, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinases (IC₅₀ = 7, 20, 1.3, 0.7, & 8.5 nM for PKA, CAMK, MLCK, PKC, & PKG, respectively).
420320 Sigma-AldrichKT5720 - CAS 108068-98-0 - Calbiochem
KT5720, CAS 108068-98-0, is a cell-permeable, potent, specific, reversible, ATP-competitive inhibitor of protein kinase A (Ki = 56 nM). Has no significant effect on PKC, PKG & MLCK.
