Millipore Sigma Vibrant Logo

MAB3773 Anti-Annexin I Antibody, clone 6E4/3

Anti-Annexin I Antibody, clone 6E4/3 detects level of Annexin I & has been published & validated for use in ELISA, IF & WB.

Anti-Annexin I Antibody, clone 6E4/3: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: ANXA1, LPC1, Annexin-1, Chromobindin-9, ANX1, p35 UniProt Number: P04083
View Products on Sigmaaldrich.com
MAB3773
100 µg  
Recuperando precio...
No pudo obtenerse el precio
La cantidad mínima tiene que ser múltiplo de
Maximum Quantity is
Al finalizar el pedido Más información
Ahorró ()
 
—
Solicitar precio
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

      Ofertas especiales

       

      Póngase en contacto con el Servicio de Atención al Cliente

      Descripción

      Replacement Information

      Ofertas especiales

      100% Performance Guaranteed

      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HELISA, IF, WBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB3773
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Annexin I Antibody, clone 6E4/3
      Alternate Names
      • Lipocortin I
      • Calpactin II
      • Chromobindin 9
      • Phospholipase A2 Inhibitory Protein
      Background InformationAnnexin I belongs to a family of Ca2+ dependent phospholipid binding proteins. It has been implicated in the regulation of phagocytosis, cell signaling and cell proliferation.
      References
      Product Information
      FormatPurified
      PresentationPurified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25M NaCl, pH 7.6, with 0.1% sodium azide
      Quality LevelMQ100
      Applications
      ApplicationAnti-Annexin I Antibody, clone 6E4/3 detects level of Annexin I & has been published & validated for use in ELISA, IF & WB.
      Key Applications
      • ELISA
      • Immunofluorescence
      • Western Blotting
      Application NotesWestern blot

      Immunofluorescence

      ELISA

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenWhole native annexin proteins contained in a mixture of membrane proteins from human bone tissue
      Clone6E4/3
      HostMouse
      SpecificityRecognizes human Annexin I
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryAnnexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
      Gene Symbol
      • ANXA1
      • LPC1
      • Annexin-1
      • Chromobindin-9
      • ANX1
      • p35
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P04083 # Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
      SIZE: 346 amino acids; 38714 Da
      SUBUNIT: Homodimer in placenta (20%); linked by transglutamylation.
      SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm (By similarity). Cell projection, cilium (By similarity). Basolateral cell membrane (By similarity). Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages (By similarity).
      DOMAIN: SwissProt: P04083 A pair of annexin repeats may form one binding site for calcium and phospholipid.
      PTM: Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity.SIMILARITY: Belongs to the annexin family. & Contains 4 annexin repeats.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      MAB3773 04053252663307

      Productos y aplicaciones relacionados

      Related Products

      Número de referencia Descripción  
      ABC151 Anti-Annexin A1, Antibody Precios y disponibilidad
      MABS45 Anti-Annexin A1 Antibody, clone CPTC-ANXA1-2 Precios y disponibilidad

      Categorías

      Life Science Research > Antibodies and Assays > Primary Antibodies