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CBL168 Anti-CD36 Antibody, clone SM-phi

Anti-CD36 Antibody, clone SM-phi is an antibody against CD36 for use in FC, WB, IH.

Anti-CD36 Antibody, clone SM-phi: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: CD36, PAS-4, GPIV, FAT, CHDS7, GP3B, SCARB3, PASIV, GP4, GPIIIB UniProt Number: P16671
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CBL168
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFC, WB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberCBL168
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-CD36 Antibody, clone SM-phi
      Alternate Names
      • Platelet Glycoprotein IV
      References
      Product Information
      FormatPurified
      PresentationThe monoclonal was purified by affinity chromatography and gel filtration and is presented in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.
      Quality LevelMQ100
      Applications
      ApplicationAnti-CD36 Antibody, clone SM-phi is an antibody against CD36 for use in FC, WB, IH.
      Key Applications
      • Flow Cytometry
      • Western Blotting
      • Immunohistochemistry
      Application NotesStudies of platelet and monocyte receptor for thrombospondin

      Studies of platelet collagen adhesion receptor

      Flow cytometry

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenHuman tonsil cells and peripheral blood mononuclear cells
      CloneSM-phi
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityThis antibody recognizes the 90 kDa single chain membrane glycoprotein (GPIIIb) that is found on monocytes/macrophages and platelets.
      FUSION PARTNER: NS1 myeloma cell line
      IsotypeIgM
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Three alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
      Gene Symbol
      • CD36
      • PAS-4
      • GPIV
      • FAT
      • CHDS7
      • GP3B
      • SCARB3
      • PASIV
      • GP4
      • GPIIIB
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P16671 # Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport.
      SIZE: 472 amino acids; 53053 Da
      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
      PTM: N-glycosylated and O-glycosylated with a ratio of 2:1.
      DISEASE: SwissProt: P16671 # Defects in CD36 are the cause of platelet glycoprotein IV deficiency [MIM:608404]; also known as CD36 deficiency. Platelet glycoprotein IV deficiency can be divided into 2 subgroups. The type I phenotype is characterized by platelets and monocytes/macrophages exhibiting complete CD36 deficiency. The type II phenotype lacks the surface expression of CD36 in platelets, but expression in monocytes/macrophages is near normal. & Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7) [MIM:610938].
      SIMILARITY: SwissProt: P16671 ## Belongs to the CD36 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsFor use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
      Packaging Information
      Material Size100 assays
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      CBL168 04053252284922

      Documentation

      Anti-CD36 Antibody, clone SM-phi Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Anti-CD36 Antibody, clone SM-phi Certificados de análisis

      CargoNúmero de lote
      MOUSE ANTI-HUMAN CD36 MONOCLONAL ANTIBODY 2969569
      MOUSE ANTI-HUMAN CD36 MONOCLONAL ANTIBODY 2898356
      MOUSE ANTI-HUMAN CD36 MONOCLONAL ANTIBODY 2903067
      MOUSE ANTI-HUMAN CD36 MONOCLONAL ANTIBODY - 3217783 3217783
      MOUSE ANTI-HUMAN CD36 MONOCLONAL ANTIBODY - 3743864 3743864
      MOUSE ANTI-HUMAN CD36 MONOCLONAL ANTIBODY - 3862541 3862541

      Referencias bibliográficas

      Visión general referenciasPub Med ID
      Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma.
      Nath, A; Li, I; Roberts, LR; Chan, C
      Scientific reports  5  14752  2015

      Mostrar resumen       		26424075 26424075
      Membrane glycoprotein CD36: a review of its roles in adherence, signal transduction, and transfusion medicine.
      Greenwalt, D E, et al.
      Blood, 80: 1105-15 (1992)  1992

      		1381234 1381234

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      Alternative Format

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      Categorías

      Life Science Research > Antibodies and Assays > Primary Antibodies