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MABN372 Anti-CLN3 Antibody, Clone 2B8.2

This Anti-CLN3 Antibody, Clone 2B8.2 is validated for use in Western Blotting and Immunohistochemistry for the detection of CLN3.

Anti-CLN3 Antibody, Clone 2B8.2: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: CLN3, BTS UniProt Number: Q13286
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MABN372
100 µg  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN372
      DescriptionAnti-CLN3 Antibody, Clone 2B8.2
      Alternate Names
      • Battenin
      • Batten disease protein
      • Protein CLN3
      Background InformationCLN3 protein is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs).
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-CLN3 Antibody, Clone 2B8.2 is validated for use in Western Blotting and Immunohistochemistry for the detection of CLN3.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blotting Analysis: 2.0 µg/mL from a representative lot detected CLN3 in 10 µg of A431 cell lysate.
      Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected CLN3 in rat cerebellum and human thalamus tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human CLN3.
      Clone2B8.2
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Mouse
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CLN3
      • BTS
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~45 kDa observed. Uniprot describes 5 isoforms produced by alternative splicing at ~45, ~42, ~37, ~35, and ~28 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HepG2 cell lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected CLN3 in 10 µg of HepG2 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      MABN372 04055977039511