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IM86 Anti-MMP-11 (Ab-2) Mouse mAb (SL3-05)

Anti-MMP-11 (Ab-2) Mouse mAb (SL3-05): Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: Anti-ST3, Anti-Stromelysin-3, Anti-Matrix Metalloproteinase 11

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      Descripción

      Replacement Information

      Tabla espec. clave

      Host
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      Description
      Overview

      This product has been discontinued.





      Recognizes the ~55 kDa latent and the ~44 kDa active forms of MMP-11. Also recognizes two degradation products of MMP-11 at ~ 35 and ~28 kDa.
      Catalogue NumberIM86
      Brand Family Calbiochem®
      SynonymsAnti-ST3, Anti-Stromelysin-3, Anti-Matrix Metalloproteinase 11
      Application Data
      Detection of human MMP-11 by immunohistochemistry. Sample: Human placenta, fixed in formalin and paraffin-embedded. Primary antibody: Anti-MMP-11 (Ab-2) Mouse mAb (SL3-05) (Cat. No. IM86) (1 µg/ml). Detection: fluorescence.

      Detection of human MMP-11 by immunoblotting. Sample: Human MMP-11. Primary antibody: Anti-MMP-11 (Ab-2) Mouse mAb (SL3-05) (Cat. No. IM86) (0.5 µg/ml). Detection: chemiluminescence.
      References
      ReferencesWagner, S.N., et al. 1992. Diagn. Mol. Pathol. 1, 200.
      Basset, P., et al. 1990. Nature 348, 699.
      Product Information
      FormLiquid
      FormulationIn 50 mM sodium phosphate buffer, 50% glycerol.
      Positive controlHuman placenta or recombinant MMP-11 protein
      PreservativeNone
      Applications
      Key Applications Frozen Sections
      Immunoblotting (Western Blotting)
      Paraffin Sections
      Application NotesFrozen Sections (1-2 µg/ml)
      Immunoblotting (0.5-1 µg/ml)
      Paraffin Sections (1-2 µg/ml, no pre-treatment required)
      Application CommentsAlso recognizes a ~35 kDa degradation product of MMP-11. Does not recognize other MMPs. Antibody should be titrated for optimal results in individual systems.
      Biological Information
      Immunogenrecombinant, human MMP-11
      ImmunogenHuman
      CloneSL3-05
      HostMouse
      IsotypeIgG₁
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      IM86 0

      Documentation

      Anti-MMP-11 (Ab-2) Mouse mAb (SL3-05) Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Anti-MMP-11 (Ab-2) Mouse mAb (SL3-05) Certificados de análisis

      CargoNúmero de lote
      IM86

      Referencias bibliográficas

      Visión general referencias
      Wagner, S.N., et al. 1992. Diagn. Mol. Pathol. 1, 200.
      Basset, P., et al. 1990. Nature 348, 699.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-September-2007 RFH
      SynonymsAnti-ST3, Anti-Stromelysin-3, Anti-Matrix Metalloproteinase 11
      ApplicationFrozen Sections (1-2 µg/ml)
      Immunoblotting (0.5-1 µg/ml)
      Paraffin Sections (1-2 µg/ml, no pre-treatment required)
      Application Data
      Detection of human MMP-11 by immunohistochemistry. Sample: Human placenta, fixed in formalin and paraffin-embedded. Primary antibody: Anti-MMP-11 (Ab-2) Mouse mAb (SL3-05) (Cat. No. IM86) (1 µg/ml). Detection: fluorescence.

      Detection of human MMP-11 by immunoblotting. Sample: Human MMP-11. Primary antibody: Anti-MMP-11 (Ab-2) Mouse mAb (SL3-05) (Cat. No. IM86) (0.5 µg/ml). Detection: chemiluminescence.
      DescriptionPurified mouse monoclonal antibody. Recognizes the ~60 kDa MMP-II pro-enzyme and the ~47 kDa active enzyme.
      BackgroundMatrix metalloproteinases are believed to play an important role in tumor invasion and metastasis. The stromelysin-3 (MMP-11) gene is expressed specifically in stromal cells surrounding invasive breast carcinomas. The product of this gene is a member of the family of metalloproteinases enzymes that degrade the extracellular matrix. Human stromelysin-3 is localized by in situ hybridization to the long arm of chromosome 22. MMP-11 expression is found more specifically in malignant tumors than in benign ones.
      HostMouse
      Immunogen speciesHuman
      Immunogenrecombinant, human MMP-11
      CloneSL3-05
      IsotypeIgG₁
      Specieshuman
      Positive controlHuman placenta or recombinant MMP-11 protein
      FormLiquid
      FormulationIn 50 mM sodium phosphate buffer, 50% glycerol.
      Concentration Label Please refer to vial label for lot-specific concentration
      PreservativeNone
      CommentsAlso recognizes a ~35 kDa degradation product of MMP-11. Does not recognize other MMPs. Antibody should be titrated for optimal results in individual systems.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesWagner, S.N., et al. 1992. Diagn. Mol. Pathol. 1, 200.
      Basset, P., et al. 1990. Nature 348, 699.