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AB15518 Anti-Neuronal pentraxin 1 Antibody

This Anti-Neuronal pentraxin 1 Antibody is validated for use in ELISA, WB, IH for the detection of Neuronal pentraxin 1.

Anti-Neuronal pentraxin 1 Antibody: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Neuroscience Research Sub-Category: Synapse & Synaptic Biology Gene Symbol: NPTX1, DKFZp686J2446, MGC105123, NP1, NP-I UniProt Number: Q15818
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AB15518
50 µg  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MELISA, WB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB15518
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Neuronal pentraxin 1 Antibody
      Alternate Names
      • NPX1
      Background InformationNeuronal Pentraxins: A new family of putative integral membrane pentraxins or Neuronal pentraxins identified through interaction with a presynaptic snake venom toxin taipoxin. NPX1, NPX2 and NPXR (Neuronal Pentraxin Receptor), the three neuronal pentraxins represent a novel neuronal uptake pathway that may function during synapse formation and remodeling. The N-terminal half of neuronal pentraxins are 20-30% identical to previously identified pentraxins (CRP and SAP), the three neuronal pentraxins are 50% identical to each other and are significantly larger than the classical pentraxins (>50 versus 30kDa), suggesting that they may have additional novel functions. NPX1(Neuronal Pentraxin 1) a 432aa protein in mouse and rat, 430aa in human (chr 17q25). It mediates the uptake of degraded synaptic material which could play an important role in synaptic remodeling, expressed in brain.
      References
      Product Information
      FormatAffinity Purified
      PresentationLiquid in PBS with 0.1% BSA.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Neuronal pentraxin 1 Antibody is validated for use in ELISA, WB, IH for the detection of Neuronal pentraxin 1.
      Key Applications
      • ELISA
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern blot: 1-10 µg/mL using ECL.
      Immunohistochemistry: Not tested. It is recommended that the antibody be tried at 2-20 µg/mL
      ELISA: 0.5-1 µg/mL using control peptide.
      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenSynthetic peptide near the N-terminus of mouse NPX1
      HostRabbit
      SpecificityNeuronal pentraxin 1 (NPX1).
      Species Reactivity
      • Mouse
      Species Reactivity NoteThe immunogen sequence is 94% conserved in rat, and 82% in human NPX1.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryNPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system.
      Gene Symbol
      • NPTX1
      • DKFZp686J2446
      • MGC105123
      • NP1
      • NP-I
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q15818 # May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin (By similarity).
      COFACTOR: Binds 2 calcium ions per subunit (By similarity).
      SIZE: 432 amino acids; 47122 Da
      SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle (Potential).
      SIMILARITY: SwissProt: Q15818 ## Contains 1 pentaxin domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      AB15518 04053252327377

      Documentation

      Anti-Neuronal pentraxin 1 Antibody Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Anti-Neuronal pentraxin 1 Antibody Certificados de análisis

      CargoNúmero de lote
      RABBIT ANTI-NEURONAL PENTRAXIN 1 - 3256014 3256014
      RABBIT ANTI-NEURONAL PENTRAXIN 1 - 3257564 3257564
      RABBIT ANTI-NEURONAL PENTRAXIN 1 - 3476021 3476021
      RABBIT ANTI-NEURONAL PENTRAXIN 1 - 3614824 3614824
      RABBIT ANTI-NEURONAL PENTRAXIN 1 - 3840814 3840814
      RABBIT ANTI-NEURONAL PENTRAXIN 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY 2987936
      RABBIT ANTI-NEURONAL PENTRAXIN 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY 3028823
      RABBIT ANTI-NEURONAL PENTRAXIN 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2329142 2329142
      RABBIT ANTI-NEURONAL PENTRAXIN 1, AFFINITY PURIFIED, POLYCLONAL ANTIBODY 2829454

      Ficha técnica

      Cargo
      RABBIT ANTI-NEURONAL PENTRAXIN 1 AFFINITY PURIFIED