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504191 CB1 agonist ACEA - CAS 220556-69-4 - Calbiochem

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: N-(2-Chloroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide

Primary Target: CB₁ Receptor
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      Descripción

      Replacement Information

      Tabla espec. clave

      CAS #Empirical Formula
      220556-69-4C₂₂H₃₆ClNO
      Description
      Overview

      This product has been discontinued.



      A Potent and highly selective agonist for CB1 receptor. Affinity for CB1 (Ki = 1.4 nM) is more than1400-fold higher than that for CB2 (KMGK = 3100 nM) receptors.
      Catalogue Number504191
      Brand Family Calbiochem®
      SynonymsN-(2-Chloroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
      References
      ReferencesDi Marzo, V., et al. 1998. Trends Neurosci. 21, 521.
      Mechoulam, R., et al. 1994. Biochem. Pharmacol. 48, 1537.
      Pertwee, R.G. 1997. Pharmacol. Ther. 74, 129.
      Fernandez-Ruiz, J., et al. 2000. Trends Neurosci. 23, 14.
      Song, Z.H., et al. 2000. J. Pharmacol. Exp. Ther. 294, 204.
      Matsuda, L.A., et al. 1990. Nature 346, 561.
      Munro, S. et al. 1993. Nature 365, 61.
      Hillard, C.J., et al. 1999. J. Pharmacol. Exp. Ther. 289, 1427.
      Product Information
      CAS number220556-69-4
      FormClear to pale yellow liquid
      FormulationSupplied in MeOAc
      Hill FormulaC₂₂H₃₆ClNO
      Chemical formulaC₂₂H₃₆ClNO
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCB₁ Receptor
      Primary Target K<sub>i</sub>1.4 nM and 3100 nM for CB₁ and CB₂ receptors, respectively.
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      504191 0

      Documentation

      CB1 agonist ACEA - CAS 220556-69-4 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Referencias bibliográficas

      Visión general referencias
      Di Marzo, V., et al. 1998. Trends Neurosci. 21, 521.
      Mechoulam, R., et al. 1994. Biochem. Pharmacol. 48, 1537.
      Pertwee, R.G. 1997. Pharmacol. Ther. 74, 129.
      Fernandez-Ruiz, J., et al. 2000. Trends Neurosci. 23, 14.
      Song, Z.H., et al. 2000. J. Pharmacol. Exp. Ther. 294, 204.
      Matsuda, L.A., et al. 1990. Nature 346, 561.
      Munro, S. et al. 1993. Nature 365, 61.
      Hillard, C.J., et al. 1999. J. Pharmacol. Exp. Ther. 289, 1427.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision21-June-2013 JSW
      SynonymsN-(2-Chloroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
      DescriptionA Potent and highly selective agonist for CB1 receptor. Affinity for CB1 (Ki = 1.4 nM) is more than1400-fold higher than that for CB2 (Ksub>i = 3100 nM) receptors.
      FormClear to pale yellow liquid
      FormulationSupplied in MeOAc
      CAS number220556-69-4
      Chemical formulaC₂₂H₃₆ClNO
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesDi Marzo, V., et al. 1998. Trends Neurosci. 21, 521.
      Mechoulam, R., et al. 1994. Biochem. Pharmacol. 48, 1537.
      Pertwee, R.G. 1997. Pharmacol. Ther. 74, 129.
      Fernandez-Ruiz, J., et al. 2000. Trends Neurosci. 23, 14.
      Song, Z.H., et al. 2000. J. Pharmacol. Exp. Ther. 294, 204.
      Matsuda, L.A., et al. 1990. Nature 346, 561.
      Munro, S. et al. 1993. Nature 365, 61.
      Hillard, C.J., et al. 1999. J. Pharmacol. Exp. Ther. 289, 1427.