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211275 Capsaicin

An active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons.

Capsaicin: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: [(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide

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      Descripción

      Replacement Information

      Tabla espec. clave

      CAS #Empirical Formula
      404-86-4C₁₈H₂₇NO₃
      Description
      OverviewAn active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced responses in rat PC12 cells. Exhibits anti-nociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.
      Catalogue Number211275
      Brand Family Calbiochem®
      Synonyms[(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
      References
      ReferencesSingh, S., et al. 1996. J. Immunol. 157, 4412.
      Nakazawa, K., et al. 1994. Br. J. Pharmacol. 113, 296.
      Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci. 12, 517.
      Takaki, M., et al. 1994. J. Mol. Cell. Cardiol. 26, 1227.
      Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci. 11, 330.
      Pernow, B., et al. 1985. J. Immunol. 135, 8125.
      Product Information
      CAS number404-86-4
      FormWhite to pale yellow solid
      Hill FormulaC₁₈H₂₇NO₃
      Chemical formulaC₁₈H₂₇NO₃
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥98% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSRA8530000
      Safety Information
      R PhraseR: 25-41-48

      Toxic if swallowed.
      Risk of serious damage to eyes.
      Danger of serious damage to health by prolonged exposure.
      S PhraseS: 26-36/37/39-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      211275 0

      Documentation

      Capsaicin Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Capsaicin Certificados de análisis

      CargoNúmero de lote
      211275

      Referencias bibliográficas

      Visión general referencias
      Singh, S., et al. 1996. J. Immunol. 157, 4412.
      Nakazawa, K., et al. 1994. Br. J. Pharmacol. 113, 296.
      Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci. 12, 517.
      Takaki, M., et al. 1994. J. Mol. Cell. Cardiol. 26, 1227.
      Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci. 11, 330.
      Pernow, B., et al. 1985. J. Immunol. 135, 8125.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-February-2020 JSW
      Synonyms[(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
      DescriptionAn active constituent of cayenne pepper. Has excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced respones in rat pheochromocytoma cells. Exhibits antinociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.
      FormWhite to pale yellow solid
      CAS number404-86-4
      RTECSRA8530000
      Chemical formulaC₁₈H₂₇NO₃
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityEthanol
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
      Toxicity Toxic
      Merck USA index14, 1768
      ReferencesSingh, S., et al. 1996. J. Immunol. 157, 4412.
      Nakazawa, K., et al. 1994. Br. J. Pharmacol. 113, 296.
      Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci. 12, 517.
      Takaki, M., et al. 1994. J. Mol. Cell. Cardiol. 26, 1227.
      Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci. 11, 330.
      Pernow, B., et al. 1985. J. Immunol. 135, 8125.