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317638 Dipeptidylpeptidase IV Inhibitor II

Dipeptidylpeptidase IV Inhibitor II: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Primary Target: dipeptylpeptidase 2 human placenta
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      Descripción

      Replacement Information

      Tabla espec. clave

      CAS #Empirical Formula
      1258008-19-3C₁₆H₂₁N₃O₄ · HCl
      Description
      Overview

      This product has been discontinued.





      A novel acylating inhibitor for the proline-specific peptidases dipeptidylpeptidase II and dipeptidylpeptidase IV. Acts as a potent reversible inhibitor of human placenta dipeptidylpeptidase II (Ki = 3.8 µM) and porcine kidney dipeptidylpeptidase IV (Ki = 1 µM). Combines the efficacy of aminoacyl pyrrolidides and the potential transacylating capability of diacylhydroxylamines.
      Half-life in buffered solution (pH 7.6) = 24 h (30°C).
      Catalogue Number317638
      Brand Family Calbiochem®
      References
      ReferencesDemuth, H.-U., et al. 1993. FEBS Lett. 320, 23.
      Product Information
      CAS number1258008-19-3
      FormWhite solid
      Hill FormulaC₁₆H₂₁N₃O₄ · HCl
      Chemical formulaC₁₆H₂₁N₃O₄ · HCl
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary Targetdipeptylpeptidase 2 human placenta
      Primary Target K<sub>i</sub>3.8 µM
      Secondary targetporcine kidney dipeptylpeptidase 4 (IC₅₀ = 1 µM)
      Purity>90% by HPLC
      Physicochemical Information
      Peptide SequenceH-Glu-(NHO-Bz)-Pyr, HCl
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      317638 0

      Documentation

      Dipeptidylpeptidase IV Inhibitor II Certificados de análisis

      CargoNúmero de lote
      317638

      Referencias bibliográficas

      Visión general referencias
      Demuth, H.-U., et al. 1993. FEBS Lett. 320, 23.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-April-2011 RFH
      DescriptionA novel acylating inhibitor for the proline-specific peptidase dipeptidylpeptidase II and dipeptidylpeptidase IV. Acts as a potent reversible inhibitor of human placenta dipeptidylpeptidase II (Ki = 3.8 µM) and porcine kidney dipeptidylpeptidase IV (Ki = 1 µM). Combines the efficacy of aminoacyl pyrrolidides and potential transacylating capability of diacylhydroxylamines. Half-life in buffered solution (pH 7.6) = 24 h (30°C).
      FormWhite solid
      CAS number1258008-19-3
      Chemical formulaC₁₆H₂₁N₃O₄ · HCl
      Peptide SequenceH-Glu-(NHO-Bz)-Pyr, HCl
      Structure formulaStructure formula
      Purity>90% by HPLC
      SolubilityDMSO (5 mg/ml), Ethanol (5 mg/ml), and H₂O (1 mg/ml)
      Storage Protect from moisture
      Protect from light
      +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesDemuth, H.-U., et al. 1993. FEBS Lett. 320, 23.