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855068 Hydroxymethyl polystyrene (100-200 mesh), 1% DVB

Novabiochem®

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Nº CAS: 9003-70-7
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855068
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Descripción

Replacement Information

Tabla espec. clave

CAS #
9003-70-7
Descripción
Número de catálogo855068
Replaces01-64-0110
Marca de familia Novabiochem®
Alternate Names
  • Polystyrene-CH2OH (100-200 mesh)
Información preliminarThis resin is ideal for the solid phase immobilization of carboxylic acids. Less cross-linking is observed than with Merrifield resin during the attachment of diacids [1]. Reaction with a suitable phosgene equivalent converts this resin to a support suitable for the immobilization of amines [2].

Release of carboxylic acids from this support is normally effected by treatment of the resin with HF or TFMSA, or by hydrogenolysis [3]. Alcohols can be liberated by reduction with DIBAL [4] or LiBH4 [5]. Methyl esters can be produced by transesterification with MeONa [6] or Ti(OEt)4/C2H5CO2Me [7]. Carboxamides are also accessible via Lewis acid catalyzed aminolysis [8].

The product number for this product was previously 01-64-0110.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
Referencias bibliográficas
Información del producto
Número de CAS9003-70-7
Código HS 3903 90 90
Imagen fórmula estructuralImagen fórmula estructural
Quality LevelMQ200
Aplicaciones
Información biológica
Información fisicoquímica
Dimensiones
Información de materiales
Información toxicológica
Información de seguridad según el GHS
Clase de almacenamiento10 - 13 Otros liquidos y sustancias sólidas
WGKWGK 1 contamina ligeramente el agua
Información de seguridad
Declaraciones de uso del producto
Información de almacenamiento y transporte
AlmacenamientoAlmacenar por debajo de +30°C.
Información sobre embalaje
Información de transporte
Información complementaria
Especificaciones
Color (visual)white to yellow to beige
Appearance of substance (visual)beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin)0.60 - 1.60 mmol/g
Swelling Volume (in DMF)lot specific result
The polymer matrix is copoly (styrene - 1% DVB) 100 -200 mesh

Documentation

Hydroxymethyl polystyrene (100-200 mesh), 1% DVB Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Citas

Título
  • [1] J. M. Goldwasser, et al. (1978) Can. J. Chem., 56, 1562.
  • [2] D. J. Burdick, et al. (1993) Tetrahedron Lett., 34, 2589.
  • [3] J. M. Schlatter, et al. (1977) Tetrahedron Lett., 2851.
  • [4] M. J. Kurth, et al. (1994) J. Org. Chem., 59, 5862.
  • [5] J. M. Stewart & J. D. Young in 'Solid Phase Peptide Synthesis, 2nd Ed.', Rockford, Illinois, Pierce Chemical Company, 1984, pp. 92.
  • [6] R. Frenette, et al. (1994) Tetrahedron Lett., 35, 9177.
  • [7] L. T. Tietze & A. Steinmetz (1996) Angew. Chem. Int. Ed. Engl., 35, 651.
  • [8] D. R. Barn, et al. (1996) Tetrahedron Lett., 37, 3213.