Millipore Sigma Vibrant Logo

573130 InSolution™ STAT3 Inhibitor VI, S3I-201 - Calbiochem

Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
C₁₆H₁₅NO₇S

Precios y disponibilidad

Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
573130-5MG
Comprobando disponibilidad...
Disponibilidad a confirmar
Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

      Frasco de vidrio 5 mg
      Recuperando precio...
      No pudo obtenerse el precio
      La cantidad mínima tiene que ser múltiplo de
      Maximum Quantity is
      Al finalizar el pedido Más información
      Ahorró ()
       
      Solicitar precio
      Description
      OverviewA cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). The solid form of this compound (Cat. No. 573102) is also available.
      Catalogue Number573130
      Brand Family Calbiochem®
      References
      ReferencesLin, L., et al. 2009. Oncogene, 28, 961.
      Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391.
      Product Information
      FormLiquid
      FormulationA 50 mM (5 mg/274 µl) solution of STAT3 Inhibitor VI, S3I-201 (Cat. No. 573102) in DMSO.
      Hill FormulaC₁₆H₁₅NO₇S
      Chemical formulaC₁₆H₁₅NO₇S
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/38

      Irritating to eyes and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      573130-5MG 04055977190205

      Documentation

      InSolution™ STAT3 Inhibitor VI, S3I-201 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      InSolution™ STAT3 Inhibitor VI, S3I-201 - Calbiochem Certificados de análisis

      CargoNúmero de lote
      573130

      Referencias bibliográficas

      Visión general referencias
      Lin, L., et al. 2009. Oncogene, 28, 961.
      Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391.

      Licencias necesarias e Información técnica

      Cargo
      JAK/STAT Signaling Research Focus
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision01-February-2012 RFH
      DescriptionA cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.).
      FormLiquid
      FormulationA 50 mM (5 mg/274 µl) solution of STAT3 Inhibitor VI, S3I-201 (Cat. No. 573102) in DMSO.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₆H₁₅NO₇S
      Structure formulaStructure formula
      Purity≥95% by HPLC
      Storage Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Irritant
      ReferencesLin, L., et al. 2009. Oncogene, 28, 961.
      Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391.