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14-615M MINK Protein, active, 250 µg

Active, N-terminal His6-tagged, recombinant, human MINK amino acids 1-310, for use in Kinase Assays.

MINK Protein, active, 250 µg: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
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14-615M
250 µg  Also available in 10 μg size (cat#14-615) and in bulk (cat#14-615-K).
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      Descripción

      Replacement Information
      Description
      Catalogue Number14-615M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionMINK Protein, active, 250 µg
      OverviewN-terminal His6-tagged, recombinant, human MINK amino acids 1-310
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationActive, N-terminal His6-tagged, recombinant, human MINK amino acids 1-310, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed by baculovirus in Sf21 insect cells
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
      Gene Symbol
      • MINK1
      • hMINK
      • ZC3
      • MINK
      • MAP4K6
      • B55
      • hMINKbeta
      • YSK2
      • MGC21111
      Protein TargetMINK
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilySTE
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q8N4C8 # Serine/threonine kinase that may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in the development of the brain (By similarity).
      COFACTOR: Magnesium (By similarity).
      SIZE: 1332 amino acids; 149810 Da
      TISSUE SPECIFICITY: Expressed in the brain, isoform 2 is more abundant than isoform 1.
      SIMILARITY: SwissProt: Q8N4C8 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 CNH domain. & Contains 1 protein kinase domain.
      Molecular Weight38.7kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of MBP
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-615) and in bulk (cat#14-615-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      14-615M 04053252924323

      Productos y aplicaciones relacionados

      Alternative Packsize

      Número de referencia Descripción  
      14-615 MINK Protein, active, 10 µg Precios y disponibilidad

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      Categorías

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases