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557450 Ruthenium Red - CAS 11103-72-3 - Calbiochem

A blocker of transmembrane Ca2+ fluxes (IC₅₀ = 7 µM) that attenuates capsaicin-induced cation channel opening.

Ruthenium Red - CAS 11103-72-3 - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: Ammoniated Ruthenium Oxychloride, RR

Primary Target: Blocker of transmembrane Ca2+ fluxes
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      Descripción

      Replacement Information

      Tabla espec. clave

      CAS #Empirical Formula
      12790-48-6[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
      Description
      OverviewA blocker of transmembrane Ca2+ fluxes (IC50 = 7 µM) that attenuates capsaicin-induced cation channel opening. Inhibits Ca2+-induced Ca2+ release from ryanodine-sensitive intracellular Ca2+ stores. Inhibits K+-stimulated catecholamine secretion (IC50 = 6 µM).
      Catalogue Number557450
      Brand Family Calbiochem®
      SynonymsAmmoniated Ruthenium Oxychloride, RR
      References
      ReferencesMerck Index 13, 8379.
      Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656.
      Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082.
      Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940.
      Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225.
      Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651.
      Ma, J. 1993. J. Gen. Physiol. 102, 1031.
      Product Information
      CAS number12790-48-6
      ATP CompetitiveN
      FormRed-black solid
      Hill Formula[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
      Chemical formula[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetBlocker of transmembrane Ca2+ fluxes
      Primary Target IC<sub>50</sub>7 µM in blocking transmembrane Ca2+ fluxes; 6 µM inhibiting K+-stimulated catecholamine secretion
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 22

      Harmful if swallowed.
      S PhraseS: 22

      Do not breathe dust.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +15°C to +30°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      557450 0

      Documentation

      Ruthenium Red - CAS 11103-72-3 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Ruthenium Red - CAS 11103-72-3 - Calbiochem Certificados de análisis

      CargoNúmero de lote
      557450

      Referencias bibliográficas

      Visión general referencias
      Merck Index 13, 8379.
      Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656.
      Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082.
      Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940.
      Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225.
      Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651.
      Ma, J. 1993. J. Gen. Physiol. 102, 1031.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-May-2024 JSW
      SynonymsAmmoniated Ruthenium Oxychloride, RR
      DescriptionA blocker of transmembrane Ca2+ fluxes (IC50 = 7 µM) that attenuates capsaicin-induced cation channel opening. Inhibits Ca2+-induced Ca2+ release from ryanodine-sensitive intracellular Ca2+ stores. Inhibits K+-stimulated catecholamine secretion (IC50 = 6 µM).
      FormRed-black solid
      CAS number12790-48-6
      Chemical formula[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
      SolubilityH₂O or ammonia
      Storage Protect from moisture
      +15°C to +30°C
      Do Not Freeze Ok to freeze
      Toxicity Harmful
      Merck USA index14, 8300
      ReferencesMerck Index 13, 8379.
      Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656.
      Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082.
      Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940.
      Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225.
      Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651.
      Ma, J. 1993. J. Gen. Physiol. 102, 1031.