Millipore Sigma Vibrant Logo

570110 Steroidogenic Factor-1 Inhibitor, SID7970631

Steroidogenic Factor-1 Inhibitor, SID7970631: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: (R,S)-Ethyl-2(2-(2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl)-1-oxoisoquinolin-5-yl)oxypropionate, NR5A1 Inhibitor

570110
  
Recuperando precio...
No pudo obtenerse el precio
La cantidad mínima tiene que ser múltiplo de
Maximum Quantity is
Al finalizar el pedido Más información
Ahorró ()
 
—
Solicitar precio
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

       

      Póngase en contacto con el Servicio de Atención al Cliente

      Descripción

      Replacement Information

      Tabla espec. clave

      CAS #Empirical Formula
      868224-75-3C₂₄H₂₄N₂O₇
      Description
      Overview

      This product has been discontinued.





      A cell-permeable isoquinolinone compound that potently inhibits SF-1 functional activity (IC50 = 16 nM and 260 nM for SF-1 triggered luciferase expression in HEK293T-full length SF-1 and CHO-K1-chimera SF-1 cells) with excellent selectivity over the liver receptor homolog-1 (LRH-1, NR5A2).
      Catalogue Number570110
      Brand Family Calbiochem®
      Synonyms(R,S)-Ethyl-2(2-(2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl)-1-oxoisoquinolin-5-yl)oxypropionate, NR5A1 Inhibitor
      References
      ReferencesMadoux, F., et al. 2008. Mol. Pharmacol. 73, 1776.
      Product Information
      CAS number868224-75-3
      FormWhite solid
      Hill FormulaC₂₄H₂₄N₂O₇
      Chemical formulaC₂₄H₂₄N₂O₇
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      570110 0

      Documentation

      Steroidogenic Factor-1 Inhibitor, SID7970631 Certificados de análisis

      CargoNúmero de lote
      570110

      Referencias bibliográficas

      Visión general referencias
      Madoux, F., et al. 2008. Mol. Pharmacol. 73, 1776.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-April-2011 RFH
      Synonyms(R,S)-Ethyl-2(2-(2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl)-1-oxoisoquinolin-5-yl)oxypropionate, NR5A1 Inhibitor
      DescriptionA cell-permeable isoquinolinone compound that potently inhibits SF-1/NR5A1 transcription activity (IC50 = 16 nM in a SFRE-driven reporter assay using HEK 293T cells expressing full-length SF-1). Reported to exhibit great aqueous solubility (140 µM in potassium phosphate buffer, pH 7.4) and excellent selectivity over the closely related transcription factor LRH-1/NR5A2.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number868224-75-3
      Chemical formulaC₂₄H₂₄N₂O₇
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month.
      Toxicity Standard Handling
      ReferencesMadoux, F., et al. 2008. Mol. Pharmacol. 73, 1776.