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  • Conformation-Specific Antibodies | Life Science Research | Merck

    A number of important diseases seem to involve dysfunction in the 3-dimensional structure of specific cellular proteins. Antibodies that target specific 3 dimensional conformations are extremely valuable in understanding disease states and etiology. These antibodies can be made in a variety of methods, but are not easy to make. EMD Millipore provides a number of these conformation specific antibodies for neurodegenerative and cancer disease research.
  • Antibody Development and Validation | Life Science Research | Merck

    At Merck, we have the advantage of having an entire cell analysis technology development team in-house. To support our multi-step, multi=application validation process, we have a tissue and blot library with over 1300 lysates, allowing us to precisely determine each antibody's specificity. We can obtain accurate data faster and accurately using confocal microscopes and high-throughput IHC instruments. Before releasing the antibody to manufacturing, we ensure that our antibodies meet our strictest specifications. Only antibodies that pass our stringent review are made available to customers. Once produced and released for sale, we support customers' research efforts with a highly specialized team of technical support scientists and field engineers.
  • Loss of Proteostasis | Life Science Research | Merck

    Hallmarks of Aging Loss of Proteostasis. Learn how loss of protein stability contributes to the aging process. Discover how Merck's autophagy detection solutions enable precise visualization of autophagosome formation under different in live cells and via in vitro analysis.